Evidence map›Paper›PMID 31938137›Full record

ArticleInternational journal of clinical and experimental pathology2018

EphA10 and EphB3 are prognostic markers in gallbladder squamous cell/adenosquamous carcinomas and adenocarcinomas.

Hai-Xiong Yan, Qing-Long Li, Wen-Wu Cai, Da Tang, Biao Wang, Xiang Liu, Zhi-De Liu, Zhu-Lin Yang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Comparative Outcomes of Adenosquamous Carcinoma of the Gallbladder: an Analysis of the National Cancer Database.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hai-Xiong YanDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Qing-Long LiDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Wen-Wu CaiDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Da TangDepartment of General Surgery, The Third Xiangya Hospital, Central South University Changsha, Hunan, China.
Biao WangDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Xiang LiuDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Zhi-De LiuDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Zhu-Lin YangDepartment of General Surgery, The Second Xiangya Hospital, Central South University Changsha, Hunan, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSquamous cell/adenosquamous carcinomas (SC/ASC) are rare subtypes of gallbladder cancers (GBCs). Clinical characteristics of SC/ASC have not been well documented, and no biological markers of GBC carcinogenesis, progression and prognosis are available.

methodsWe detected EphA10 and EphB3 expression in 69 SC/ASCs and 146 adenocarcinomas (ACs) with EnVision immunohistochemistry.

resultsThe percentage of cases with a patient age of > 45 years, lymph node metastasis and invasion was significantly higher in the SCs/ASCs compared with the ACs (

conclusionsThe present study indicates that positive EphA10 and negative EphB3 expression are closely associated with the pathogenesis, clinical, pathological and biological behaviors, and poor prognosis in gallbladder cancer.

Indexed as

adenosquamous carcinomasEphA10EphB3Gallbladder neoplasmimmunohistochemistrysquamous cell carcinoma

Identifiers

PMID31938137
PMCPMC6958000
OpenAlexW3027212521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.