Evidence map›Paper›PMID 31938135›Full record

ArticleInternational journal of clinical and experimental pathology2018

miR-483-3p promotes proliferation and migration of neuroblastoma cells by targeting PUMA.

Kai Wu, Jianjun Wang, Jixian He, Qinming Chen, Liucheng Yang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Microrna Expression inMicroRNA (Shariqah, United Arab Emirates) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kai WuDepartment of Surgery, Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China.
Jianjun WangDepartment of Surgery, Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China.
Jixian HeDepartment of Surgery, Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China.
Qinming ChenDepartment of Surgery, Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China.
Liucheng YangDepartment of Surgery, Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China.
Zhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extra-cranial solid tumor in infants and children and accounts for about 15% of deaths from childhood cancers. MicroRNAs (miRNAs) have been shown to play an important role in several cellular processes, such as cell proliferation, apoptosis, invasion, metastasis and angiogenesis, and therefore have been implicated in cancer progression. miR-483-3p is associated with neuroblastoma and is found to function as an 'onco-miR' in some malignancies. However, its role in neuroblastoma remains poorly understood. In this study, we confirmed that miR-483-3p is overexpressed in neuroblastoma tissue when compared with normal tissue and miR-483-3p expression is also associated with tumor stage. Overexpression of miR-483-3p substantially enhanced cell proliferation, migration, and invasion of neuroblastoma cells. miR-483-3p also promoted tumor growth of neuroblastoma

Indexed as

metastasismiR-483-3pneuroblastomaproliferationPUMA

Identifiers

PMID31938135
PMCPMC6958035
OpenAlexW3027166895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.