ArticleInternational journal of clinical and experimental pathology2018
Characteristics of bile microbiota in liver transplant recipients with biliary injury.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Landscape in the gallbladder mycobiome and bacteriome of patients undergoing cholelithiasis with chronic cholecystitis.Frontiers in microbiology · 2023Article
- ABO-Incompatible Liver Transplantation under the Desensitization Protocol with Rituximab: Effect on Biliary Microbiota and Metabolites.Journal of clinical medicine · 2022Article
- Biliary Diseases from the Microbiome Perspective: How Microorganisms Could Change the Approach to Benign and Malignant Diseases.Microorganisms · 2022Review
- Bile microbiota: new insights into biliary complications in liver transplant recipients.Annals of translational medicine · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify the species and abundance of microbes in the bile of patients with biliary injury after liver transplantation. To explore the potential microbial involvement, we evaluated the differences in biliary microbiota in patients with and without biliary injury after liver transplantation.
methodsBile was collected by percutaneous transhepatic cholangiography drainage from 5 liver transplant recipients with biliary injury (case group) and from the T-tube in 4 liver transplant recipients without biliary injury (control group). 16S rRNA sequencing was performed on the bile samples.
resultsThe biliary bacterial phyla in patients after liver transplantation were
conclusionThis is the first bile microbiota report using high-throughput 16S rRNA gene sequencing of bile material in liver transplant recipients. There were significant differences in bacterial abundance between patients with and without biliary tract injury after liver transplantation but no significant differences in the diversity. KEGG analysis showed that there were differences in metabolic pathways between the two groups.
Indexed as
Identifiers
31938134PMC6958004W3003523451What OpenQuestion holds
Registered trials
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