ArticleInternational journal of clinical and experimental pathology2018
Smurf1-positive expression indicates favorable survival for resected non-small cell lung cancer patients.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Suppressing SMURF1 to preserve GSTM2: An approach to reducing gastric cancer aggressivenessHistology and histopathology · 2026Article
- Pharmacological Modulation of Ubiquitin-Proteasome Pathways in Oncogenic Signaling.International journal of molecular sciences · 2021Review
- SMURF1, a promoter of tumor cell progression?Cancer gene therapy · 2021Review
- L1CAM-positive expression is associated with poorer survival outcomes in resected non-small cell lung cancer patients.International journal of clinical and experimental pathology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently studies have found that Smurf1 inhibits PIPKIγ-promoted lung cancer cell growth, tumorigenesis, and drug resistance through mediating the ubiquitination and degradation of PIPKIγi2. However, at present there is no study focused on the expression of Smurf1 protein as well as correlations among Smurf1 and lung cancer patients' survival. Therefore, we appraised Smurf1 expression by immmunohistochemistry and analyzed associations with prognosis in resected non-small cell lung cancer (NSCLC) patients. Overall, a number of 175 patients were enrolled in our study. We found that about 53 (30.2%) out of 175 NSCLC patients had Smurf1-pisitive expression. Smurf1-positive expression was significantly associated with lower lymph node metastasis (
Indexed as
Identifiers
31938124PMC6957962W3006093153What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.