ArticleInternational journal of clinical and experimental pathology2018
Elevated level of Vav1 was correlated with advanced biological behavior and poor prognosis in patients with gastric cancer.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Review
- Identification of prognostic alternative splicing events in sarcoma.Scientific reports · 2021Article
- Screening to Identify an Immune Landscape-Based Prognostic Predictor and Therapeutic Target for Prostate Cancer.Frontiers in oncology · 2021Article
- RhoA G17E/Vav1 Signaling Induces Cancer Invasion via Matrix Metalloproteinase-9 in Gastric Cancer.Technology in cancer research & treatmentArticle
- Identification of Immune Infiltrating Cell-Related Biomarkers in Early Gastric Cancer Progression.Technology in cancer research & treatmentArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vav1 play key roles in the progression of human cancer. However, the role of Vav1 in gastric cancer (GC) remains to be elucidated. The present study aimed to investigate the potential relevance of the clinicopathological characteristics and prognostic significance of Vav1 in GC patients.
methodsThe protein expression of Vav1 was analyzed by immunohistochemistry in formalin-fixed samples obtained from 105 GC patients.
resultsPositive Vav1 expression was correlated with larger tumor size and more lymph node metastasis (
conclusionVav1 performs important functions in the aggressiveness of GC, and Vav1 may serve as a novel prognostic factor in GC.
Indexed as
Identifiers
31938123PMC6957931W3027895400What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.