Evidence map›Paper›PMID 31938107›Full record

ArticleInternational journal of clinical and experimental pathology2018

Detecting the location and significance of Ezrin protein expression in hepatocellular carcinoma.

Yan Wang, Shaochen Jiang, Zhongliang Cao, Chunxiao Xie, Weidong Li, Yibing Ma, Jinhui Zhang, Lijuan Lin

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yan WangInstitute of Molecular Medicine, Medical College of Eastern Liaoning University Dandong 118003, China.
Shaochen JiangLiaoning Coloproctological Hospital, The Third Affiliated Hospital of Liaoning University of Traditional Medicine Shenyang 110000, China.
Zhongliang CaoDepartment of General Surgery, Dandong Center Hospital Dandong 118002, China.
Chunxiao XieDepartment of Emergency, Dandong First Hospital Dandong 118001, China.
Weidong LiDepartment of Anesthesiology, Dandong First Hospital Dandong 118001, China.
Yibing MaDepartment of Pathology, Dandong Center Hospital Dandong 118002, China.
Jinhui ZhangInstitute of Molecular Medicine, Medical College of Eastern Liaoning University Dandong 118003, China.
Lijuan LinInstitute of Molecular Medicine, Medical College of Eastern Liaoning University Dandong 118003, China.
Eastern Liaoning University · CNPudong Medical Center · CNWuhan Wudong Hospital · CNAffiliated Hospital of Liaoning University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the characteristics of localization and prognostic implication of Ezrin expression in HCC, 92 cases of HCC meeting strict follow-up criteria were selected for immunohistochemical staining of Ezrin protein. Correlations between Ezrin expression and clinicopathological features of HCC were evaluated using Chi-square tests, survival rates were calculated using the Kaplan-Meier method, and the relationship between prognostic factors and patient overallsurvival was analyzed using Cox proportional hazard analysis. In results, Ezrin protein was mainly expressed in the inner side of the cell membrane of the adjacent non tumor tissues, and diffusely expressed in cytoplasm of HCC tissues. There was an obviously difference between the benign and malignant tissues about the location of Ezrin expression. Ezrin strong-expression rates were significantly higher in HCC samples compared with the adjacent non tumor tissues (

Indexed as

Ezrinhepatocellular carcinomalocalizationsurvival

Identifiers

PMID31938107
PMCPMC6957936
OpenAlexW3012627278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.