ArticleInternational journal of clinical and experimental pathology2018
Expression of E-cadherin, vimentin and β-catenin in ameloblastoma and association with clinicopathological characteristics of ameloblastoma.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Review
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- Maxillary neoplasms in four dromedary camels.Frontiers in veterinary science · 2023Article
- Inhibition of L-type voltage-gated calcium channel-mediated CaCell proliferation · 2022Article
- Impact of N-Terminal Tags on De Novo Vimentin Intermediate Filament Assembly.International journal of molecular sciences · 2022Article
- Odontogenic carcinosarcoma with dentinoid: a rare case report.The Journal of international medical research · 2021Article
- Comparison of Snail1, ZEB1, E-Cadherin Expression Levels in HPV-Induced Cervical Cancer.Iranian journal of public health · 2020Article
- Influence of Heat Treatment on Muscle Recovery after Skeletal Muscle Injury in Rats: Histological and Immunohistochemical Studies.Journal of microscopy and ultrastructureArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAmeloblastoma shows invasive growth and is susceptible to recurrence. This study aimed to detect the expression of E-Cadherin, Vimentin and β-Catenin (proteins related to epithelial mesenchymal transformation (EMT) in the ameloblastoma and to explore association with clinicopathological characteristics of ameloblastoma.
methodsImmunohistochemistry was employed to detect the protein expression of E-Cadherin, Vimentin and β-Catenin in the ameloblastoma, and its association with clinicopathological characteristics of ameloblastoma was further evaluated.
resultsE-Cadherin expression was reduced or absent on the membrane of the peripheral columnar and cubic epithelial cells; Vimentin expression was high in the interstitium as well as epithelial cells in ameloblastoma; E-Cadherin expression was negatively related to Vimentin expression. β-catenin expression on the membrane of ameloblastoma epithelial cells reduced, but its ectopic expression was observed in the cytoplasm and/or nucleus.
conclusionEMT related proteins E-Cadherin, β-catenin and Vimentin are involved in the occurrence and development of ameloblastoma and these proteins can be used as biomarkers of invasiveness of ameloblastoma.
Indexed as
Identifiers
31938101PMC6957967W3027265163What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.