Evidence map›Paper›PMID 31938053›Full record

ArticleTheranostics2020

Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE

Chuanrui Ma, Ronglin Xia, Shu Yang, Lipei Liu, Jing Zhang, Ke Feng, Yuna Shang, Jingtian Qu, Lingwei Li, Ning Chen and 8 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of Yangxin Recipe in Combination with Conventional Western Medicine in Treatment of Angina Pectoris of Coronary Heart Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Peroxynitrite regulates ER stress-mediated CaJournal of translational medicine · 2025
    Article
  14. Review
  15. IGF2BP1-Mediates mActa Cardiologica Sinica · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Chuanrui MaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ronglin XiaTianjin Hospital, Tianjin, China.
Shu YangDepartment of Endocrinology, The Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, China.
Lipei LiuCollege of Life Sciences, Nankai University, Tianjin; China.
Jing ZhangState Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ke FengCollege of Life Sciences, Nankai University, Tianjin; China.
Yuna ShangCollege of Life Sciences, Nankai University, Tianjin; China.
Jingtian QuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Lingwei LiFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ning ChenSchool of Materials Science and Engineering, Tianjin University, Tianjin, China.
Shixin XuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wenwen ZhangTianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China.
Jingyuan MaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jihong HanCollege of Life Sciences, Nankai University, Tianjin; China.
Yuanli ChenSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Xiaoxiao YangSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Yajun DuanSchool of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Guanwei FanFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CNHefei University of Technology · CNNankai University · CNJinan University · CNTianjin Central Hospital of Gynecology Obstetrics · CNTianjin Hospital · CNTianjin University · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAtherosclerosisCell AdhesionCell ProliferationFoam CellsHumansHuman Umbilical Vein Endothelial CellsIsoflavonesKruppel-Like Factor 4Kruppel-Like Transcription FactorsMaleMiceMice, Inbred C57BLMice, Knockout, ApoEMyocytes, Smooth MuscleScavenger Receptors, Class AformononetinIsoflavonesKLF4 protein, humanKlf4 protein, mouseKruppel-Like Factor 4Kruppel-Like Transcription FactorsMsr1 protein, mouseScavenger Receptors, Class Aatherosclerosischolesterol uptakefoam cellsformononetininflammationKrüppel-like factor 4Scavenger receptor A1

Identifiers

PMID31938053
PMCPMC6956811
OpenAlexW2993607665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.