Evidence map›Paper›PMID 31938048›Full record

ArticleTheranostics2020

PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness.

Mohamed Hamyeh, Florence Bernex, Romain M Larive, Aurélien Naldi, Serge Urbach, Joelle Simony-Lafontaine, Carole Puech, William Bakhache, Jérome Solassol, Peter J Coopman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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  12. Biomedicines · 2022
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  13. Review
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  15. Review
  16. Increased intracellular ClTheranostics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Mohamed HamyehIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Florence BernexIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Romain M LariveIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Aurélien NaldiDynamique des Interactions Membranaires Normales et Pathologiques, CNRS, UMR5235, Montpellier, France.
Serge UrbachInstitute of Functional Genomics, Montpellier, France.
Joelle Simony-LafontaineIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Carole PuechIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
William BakhacheIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Jérome SolassolIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Peter J CoopmanIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Wiljan J A J HendriksDepartment of Cell Biology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.
Gilles FreissIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, F-34298, France.
Université de Montpellier · FRCentre National de la Recherche Scientifique · FRInserm · FRInstitut de Recherche en Cancérologie de Montpellier · FRInstitut de Génomique Fonctionnelle · FRLaboratory of Pathogens and Host Immunity · FRRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical data suggest that the protein tyrosine phosphatase PTPN13 exerts an anti-oncogenic effect. Its exact role in tumorigenesis remains, however, unclear due to its negative impact on FAS receptor-induced apoptosis.

Indexed as

Mammary Neoplasms, ExperimentalTriple Negative Breast NeoplasmsAnimalsCell Line, TumorCell MovementCell ProliferationCell Transformation, NeoplasticEpithelial-Mesenchymal TransitionErb-b2 Receptor Tyrosine KinasesFemaleHumansIntercellular JunctionsMiceMice, NudeMice, TransgenicNeoplasm InvasivenessERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesProtein Tyrosine Phosphatase, Non-Receptor Type 13PTPN13 protein, humanBreast cancercell junctionsmetastasesPTPN13.Transgenic miceTyrosine Phosphatase

Identifiers

PMID31938048
PMCPMC6956795
OpenAlexW2992120628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.