ArticleCommunications biology2020
Endoplasmic reticulum-derived bodies enable a single-cell chemical defense in Brassicaceae plants.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Cell-type-specific gating of gene regulatory modules as a hallmark of early immune responses in Arabidopsis leaves.The New phytologist · 2026Article
- Selective degradation processes in plants are not limited to autophagy.Plant cell reports · 2026Review
- Arabidopsis MYB47 and MYB95 transcription factors regulate jasmonate-inducible ER-body formation.Communications biology · 2025Article
- Arabidopsis MEB3 functions as a vacuolar metal transporter to regulate iron accumulation in roots.Frontiers in plant science · 2025Article
- ATML1 Regulates the Differentiation of ER Body-Containing Large Pavement Cells in Rosette Leaves of Brassicaceae Plants.Plant & cell physiology · 2024Article
- Root-based inorganic carbon uptake increases the growth ofFrontiers in plant science · 2024Article
- Differential contributions of two domains of NAI2 to the formation of the endoplasmic reticulum body.Frontiers in plant science · 2023Article
- MYC transcription factors coordinate tryptophan-dependent defence responses and compromise seed yield in Arabidopsis.The New phytologist · 2022Article
- Integrated omics reveal novel functions and underlying mechanisms of the receptor kinase FERONIA in Arabidopsis thaliana.The Plant cell · 2022Article
- Specialized endoplasmic reticulum-derived vesicles in plants: Functional diversity, evolution, and biotechnological exploitation.Journal of integrative plant biology · 2022Review
- RNA Sequencing ofInternational journal of molecular sciences · 2022Review
- Root growth inhibition and ultrastructural changes in radish root tips after treatment with aqueous extracts of Fallopia japonica and F. ×bohemica rhizomes.Protoplasma · 2022Article
- The Cellular and Subcellular Organization of the Glucosinolate-Myrosinase System against Herbivores and Pathogens.International journal of molecular sciences · 2022Review
- A rich and bountiful harvest: Key discoveries in plant cell biology.The Plant cell · 2022Review
- Fungal endophytes of Brassicaceae: Molecular interactions and crop benefits.Frontiers in plant science · 2022Review
- Review
- Texture feature extraction from microscope images enables a robust estimation of ER body phenotype in Arabidopsis.Plant methods · 2021Article
- Jasmonate regulates the FAMA/mediator complex subunit 8-THIOGLUCOSIDE GLUCOHYDROLASE 1 cascade and myrosinase activity.Plant physiology · 2021Article
- Retrograde sulfur flow from glucosinolates to cysteine inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- The Arabidopsis transcription factor NAI1 activates thePlant signaling & behavior · 2021Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brassicaceae plants have a dual-cell type of chemical defense against herbivory. Here, we show a novel single-cell defense involving endoplasmic reticulum (ER)-derived organelles (ER bodies) and the vacuoles. We identify various glucosinolates as endogenous substrates of the ER-body β-glucosidases BGLU23 and BGLU21. Woodlice strongly prefer to eat seedlings of bglu23 bglu21 or a glucosinolate-deficient mutant over wild-type seedlings, confirming that the β-glucosidases have a role in chemical defense: production of toxic compounds upon organellar damage. Deficiency of the Brassicaceae-specific protein NAI2 prevents ER-body formation, which results in a loss of BGLU23 and a loss of resistance to woodlice. Hence, NAI2 that interacts with BGLU23 is essential for sequestering BGLU23 in ER bodies and preventing its degradation. Artificial expression of NAI2 and BGLU23 in non-Brassicaceae plants results in the formation of ER bodies, indicating that acquisition of NAI2 by Brassicaceae plants is a key step in developing their single-cell defense system.
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