ArticleScientific reports2020
ToF-SIMS 3D imaging unveils important insights on the cellular microenvironment during biomineralization of gold nanostructures.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
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- Digital Transformation in Toxicology: Improving Communication and Efficiency in Risk Assessment.ACS omega · 2023Review
- Advancements in ToF-SIMS imaging for life sciences.Frontiers in chemistry · 2023Review
- A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry.International journal of molecular sciences · 2022Article
- Applications of stable isotopes in MALDI imaging: current approaches and an eye on the future.Analytical and bioanalytical chemistry · 2021Review
- Mussel-Inspired Gold Nanoparticle and PLGA/L-Lysine-g-Graphene Oxide Composite Scaffolds for Bone Defect Repair.International journal of nanomedicine · 2021Article
- Indocyanine Green-Based Theranostic Nanoplatform for NIR Fluorescence Image-Guided Chemo/Photothermal Therapy of Cervical Cancer.International journal of nanomedicine · 2021Article
- Spatially resolved 3D metabolomic profiling in tissues.Science advances · 2021Article
- Nanomedicine-Based Therapeutics to Combat Acute Lung Injury.International journal of nanomedicine · 2021Review
- Inhibiting Cell Viability and Motility by Layer-by-Layer Assembly and Biomineralization.ACS omega · 2020Article
- The Vitamin A and D Exposure of Cells Affects the Intracellular Uptake of Aluminum Nanomaterials and its Agglomeration Behavior: A Chemo-Analytic Investigation.International journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biomolecular imaging of cell-nanoparticle (NP) interactions using time-of-flight secondary ion mass spectrometry (ToF-SIMS) represents an evolving tool in nanotoxicology. In this study we present the three dimensional (3D) distribution of nanomaterials within biomolecular agglomerates using ToF-SIMS imaging. This novel approach was used to model the resistance of human alveolar A549 cells against gold (Au) ion toxicity through intra- and extracellular biomineralization. At low Au concentrations (≤1 mM HAuCl
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