Evidence map›Paper›PMID 31937649›Full record

ArticlemBio2020

Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS.

Elizabeth A DelMain, Derek E Moormeier, Jennifer L Endres, Rebecca E Hodges, Marat R Sadykov, Alexander R Horswill, Kenneth W Bayles

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Journal of bacteriology · 2025
    Article
  4. Review
  5. Microorganisms · 2025
    Review
  6. Frontiers in microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Micrococcal Nuclease stimulatesFrontiers in cellular and infection microbiology · 2021
    Article
  17. Article
  18. Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elizabeth A DelMainDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Derek E MoormeierDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Jennifer L EndresDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Rebecca E HodgesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Marat R SadykovDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Alexander R HorswillDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0002-5568-0096
Kenneth W BaylesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA kbayles@unmc.edu.
University of Nebraska Medical Center · USUniversity of Colorado Denver · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2009 to 2023
$32.1M
The molecular control of bacterial programmed cell deathR01AI125589 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2016 to 2020
$1.9M
NIAID NIH HHS P01 AI083211NIAID NIH HHS R01 AI125589
6 · The paper itself

Abstract

The intricate process of biofilm formation in the human pathogen

Indexed as

Gene Expression Regulation, BacterialAllelesBacterial ProteinsBiofilmsProtein KinasesStaphylococcus aureusTranscription FactorsVirulenceVirulence FactorsBacterial ProteinsProtein KinasesSaeR protein, Staphylococcus aureusSaeS protein, Staphylococcus aureusTranscription FactorsVirulence Factorsbiofilmsdevelopmental biologygene regulationStaphylococcus aureusstochastic expressionvirulence factors

Identifiers

PMID31937649
PMCPMC6960292
OpenAlexW2999269994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.