Evidence map›Paper›PMID 31937647›Full record

ArticlemBio2020

Multiple Alternative Carbon Pathways Combine To Promote Candida albicans Stress Resistance, Immune Interactions, and Virulence.

Robert B Williams, Michael C Lorenz

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
1.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 86 citations in OpenAlex.

  1. Exometabolome variation in the fungal pathogen of humansApplied and environmental microbiology · 2026
    Article
  2. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Article
  4. Review
  5. bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Expression of 1,3-β-glucan synthase subunits inAntimicrobial agents and chemotherapy · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Current research in microbial sciences · 2024
    Article
  17. Article
  18. The FVirulence · 2023
    Article
  19. Infection and immunity · 2023
    Article
  20. Catalase produced bymSphere · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert B WilliamsDepartment of Microbiology and Molecular Genetics, University of Texas McGovern Medical School and the MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, USA.ORCID 0000-0002-3600-1537
Michael C LorenzDepartment of Microbiology and Molecular Genetics, University of Texas McGovern Medical School and the MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, Texas, USA Michael.Lorenz@uth.tmc.edu.ORCID 0000-0002-7881-8027
The University of Texas MD Anderson Cancer Center · US

Funding

Roles of acetate metabolism in the virulence of Candida albicansR01AI075091 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LORENZ, MICHAEL C · 2007 to 2017
$4.0M
Characterization of novel virulence factors in CandidaR01AI143304 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LORENZ, MICHAEL C · 2019 to 2024
$2.6M
Molecular Basis of Infectious Diseases Training GrantT32AI055449 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LORENZ, MICHAEL C · 2005 to 2025
$2.6M
Mechanisms of Candida-induced phagolysosome neutralizationR21AI147631 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LORENZ, MICHAEL C · 2019 to 2020
$426k
NIAID NIH HHS R01 AI075091NIAID NIH HHS R01 AI143304NIAID NIH HHS R21 AI147631NIAID NIH HHS T32 AI055449
6 · The paper itself

Abstract

The phagocytic cells of the innate immune system are an essential first line of antimicrobial defense, and yet

Indexed as

Metabolic Networks and PathwaysOxidative StressAnimalsCandida albicansCarbonCell LineFungal ProteinsGlucoseHost-Pathogen InteractionsMacrophagesMicePhagosomesVirulenceCarbonFungal ProteinsGlucoseamino acidCandidacarboxylic acidfungal pathogenesishost-pathogen interactionsmacrophagemetabolismN-acetylglucosaminenutritional immunitystressvirulence

Identifiers

PMID31937647
PMCPMC6960290
OpenAlexW2999032278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.