Evidence map›Paper›PMID 31936863›Full record

ArticleGenes2020

Genome-Wide Association Study and Subsequent Exclusion of

Erin N Hales, Christina Esparza, Sichong Peng, Anna R Dahlgren, Janel M Peterson, Andrew D Miller, Carrie J Finno

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. A missense mutation in theFrontiers in neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Erin N HalesDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.ORCID 0000-0002-8007-6552
Christina EsparzaDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.
Sichong PengDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.
Anna R DahlgrenDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.
Janel M PetersonDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.ORCID 0000-0001-8907-8581
Andrew D MillerDepartment of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA.ORCID 0000-0001-6350-5581
Carrie J FinnoDepartment of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.ORCID 0000-0001-5924-0234
University of California, Davis · USCornell University · US

Funding

NIH HHS 5K01OD015134NIH HHS L40 TR001136
6 · The paper itself

Abstract

Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder of unknown etiology. Clinical signs of neurological deficits develop within the first year of life in vitamin E (vitE) deficient horses. A genome-wide association study (GWAS) was carried out using 670,000 SNP markers in 27 case and 42 control Quarter Horses. Two markers, encompassing a 2.5 Mb region on ECA7, were associated with the phenotype (

Indexed as

AnimalsDisease Models, AnimalFemaleGenome-Wide Association StudyHomozygoteHorse DiseasesHorsesMaleMiceMice, Inbred C3HMice, KnockoutNerve Tissue ProteinsNeuroaxonal DystrophiesPhenotypeVitamin EVitamin E DeficiencyAtcay protein, mouseNerve Tissue ProteinsVitamin Ealpha-tocopherolCayman Ataxiaequine degenerative myeloencephalopathygeneticshorsevitamin E

Identifiers

PMID31936863
PMCPMC7016928
OpenAlexW2999669948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.