Evidence map›Paper›PMID 31936796›Full record

ArticleGenes2020

Androgen Receptor Gene Variants in New Cases of Equine Androgen Insensitivity Syndrome.

Daniel A F Villagomez, Eastman G Welsford, W Allan King, Tamas Revay

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Impaired Reproductive Function in Equines: From Genetics to Genomics.Animals : an open access journal from MDPI · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Daniel A F VillagomezDepartment of Biomedical Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-8518-937X
Eastman G WelsfordDepartment of Biomedical Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
W Allan KingDepartment of Biomedical Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Tamas RevayDepartment of Biomedical Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
University of Guelph · CAUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the domestic horse; failure of normal masculinization and virilization due to deficiency of androgenic action leads to a specific disorder of sexual development known as equine androgen insensitivity syndrome (AIS). Affected individuals appear to demonstrate an incoherency between their genetic sex and sexual phenotype; i.e., XY-sex chromosome constitution and female phenotypic appearance. AIS is well documented in humans. Here we report the finding of two novel genetic variants for the AR-gene identified in a Tennessee Walking Horse and a Thoroughbred horse mare; each in individual clinical cases of horse AIS syndrome.

Indexed as

Androgen-Insensitivity SyndromeAnimalsFemaleGenetic VariationHorsesMaleMutationPhenotypeReceptors, AndrogenSequence Analysis, ProteinSex ChromosomesVirilismReceptors, Androgenandrogen insensitivityandrogen receptorAR-gene mutationhorse

Identifiers

PMID31936796
PMCPMC7017088
OpenAlexW2999502842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.