Evidence map›Paper›PMID 31936722›Full record

ArticleMicroorganisms2020

Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host.

Alejandra Chávez-Carbajal, María Luisa Pizano-Zárate, Fernando Hernández-Quiroz, Guillermo Federico Ortiz-Luna, Rosa María Morales-Hernández, Amapola De Sales-Millán, María Hernández-Trejo, Angelina García-Vite, Luis Beltrán-Lagunes, Carlos Hoyo-Vadillo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Therapeutic Effects of ProbioticFood science & nutrition · 2026
    Article
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  11. The Gut Microbiota-Related Antihyperglycemic Effect of Metformin.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alejandra Chávez-CarbajalDepartamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México 07360, Mexico.
María Luisa Pizano-ZárateDepartamento de Nutrición y Bioprogramación, Instituto Nacional de Perinatología, Ciudad de México 11000, Mexico.ORCID 0000-0002-2190-6421
Fernando Hernández-QuirozDepartamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México 07360, Mexico.
Guillermo Federico Ortiz-LunaDepartamento de Peri y Posmenopausia, Instituto Nacional de Perinatología, Ciudad de México 11000, Mexico.
Rosa María Morales-HernándezDepartamento de Nutrición y Bioprogramación, Instituto Nacional de Perinatología, Ciudad de México 11000, Mexico.
Amapola De Sales-MillánDepartamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México 07360, Mexico.ORCID 0000-0002-2527-8055
María Hernández-TrejoDepartamento de Neurolobiología del Desarrollo, Instituto Nacional de Perinatología, Ciudad de México 1100, Mexico.
Angelina García-ViteMódulo Integral de Atención al Paciente con Diabetes por Etapas, Clínica de Medicina Familiar "Gustavo A. Madero", I.S.S.S.T.E., Ciudad de México 07020, Mexico.
Luis Beltrán-LagunesJefatura de Enseñanza e Investigación, Clínica de Medicina Familiar "Gustavo A Madero", I.S.S.S.T.E., Ciudad de México 07020, Mexico.
Carlos Hoyo-VadilloDepartamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de Mexico 07360, Mexico.
Jaime García-MenaDepartamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México 07360, Mexico.ORCID 0000-0002-0595-3711
Instituto Politécnico Nacional · MXInstituto Nacional de Perinatología · MX

Funding

Consejo Nacional de Ciencia y Tecnología CONACyT-163235 INFR-2011-01Consejo Nacional de Ciencia y Tecnología FONSEC SS/IMSS/ISSSTE-CONACYT-233361Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. ISSSTEInstituto Nacional de Perinatología (539) 212250-3310-21108-04-1
6 · The paper itself

Abstract

In this work, we studied 217 Mexican subjects divided into six groups with different stages of glucose intolerance: 76 Controls (CO), 54 prediabetes (PRE), 14 T2D no medication (T2D-No-M), 14 T2D with Metformin (T2D-M), 22 T2D with polypharmacy (T2D-P), and 37 T2D with polypharmacy and insulin (T2D-P+I). We aimed to determine differences in the gut microbiota diversity for each condition. At the phylum level, we found that Firmicutes and Bacteroidetes outline major changes in the gut microbiota. The gut bacterial richness and diversity of individuals in the T2D-No-M group were lesser than other groups. Interestingly, we found a significant difference in the beta diversity of the gut microbiota among all groups. Higher abundance was found for

Indexed as

and high-throughput DNA sequencingdietgut microbiotametabolic disordersprediabetestype 2 diabetes

Identifiers

PMID31936722
PMCPMC7022408
OpenAlexW2998993844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.