Evidence map›Paper›PMID 31936670›Full record

ArticleInternational journal of molecular sciences2020

The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients.

Kazuhisa Furue, Takamichi Ito, Yuka Tanaka, Akiko Hashimoto-Hachiya, Masaki Takemura, Maho Murata, Makiko Kido-Nakahara, Gaku Tsuji, Takeshi Nakahara, Masutaka Furue

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Pharmacological Management of Psoriasis: Current Landscape and Future Perspectives.Recent advances in inflammation & allergy drug discovery · 2025
    Review
  4. Article
  5. Crosstalk between purinergic receptor P2YCellular and molecular life sciences : CMLS · 2024
    Article
  6. Article
  7. Multi-target mechanism ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Interleukin-17A and Keratinocytes in Psoriasis.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kazuhisa FurueDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Takamichi ItoDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Yuka TanakaDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Akiko Hashimoto-HachiyaResearch and Clinical Center for Yusho and Dioxin, Kyushu University Hospital, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Masaki TakemuraDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Maho MurataDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Makiko Kido-NakaharaDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Gaku TsujiResearch and Clinical Center for Yusho and Dioxin, Kyushu University Hospital, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Takeshi NakaharaDivision of Skin Surface Sensing, Department of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Masutaka FurueDepartment of Dermatology, Faculty of Medical Sciences, Kyushu University, Maidashi 3-1-1, Fukuoka 812-8582, Japan.
Kyushu University · JPKyushu University Hospital · JP

Funding

The Ministry of Health, Labour, and Welfare in Japan H30-Shokuhin-Shitei-005
6 · The paper itself

Abstract

Epidermal keratinocytes represent a rich source of C-C motif chemokine 20 (CCL20) and recruit CCR6

Indexed as

Signal TransductionCell LineChemokine CCL20ErbB ReceptorsExtracellular Signal-Regulated MAP KinasesHumansInterleukin-17JNK Mitogen-Activated Protein KinasesKeratinocytesMalep38 Mitogen-Activated Protein KinasesPhosphorylationPsoriasisUp-RegulationChemokine CCL20ErbB ReceptorsExtracellular Signal-Regulated MAP KinasesInterleukin-17JNK Mitogen-Activated Protein Kinasesp38 Mitogen-Activated Protein KinasesCCL20epidermal growth factor receptorERKIL-17AJNKkeratinocyteKoebner phenomenonp38 MAPKpsoriasisscratch injury

Identifiers

PMID31936670
PMCPMC7013594
OpenAlexW2999203501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.