Evidence map›Paper›PMID 31936605›Full record

ArticleInternational journal of molecular sciences2020

Impact of the Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma (A-PRP) and Activated Platelet-Rich Plasma (AA-PRP) in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation.

Pietro Gentile, Claudio Calabrese, Barbara De Angelis, Laura Dionisi, Jacopo Pizzicannella, Ashutosh Kothari, Domenico De Fazio, Simone Garcovich

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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  7. [Research progress on extracellular vesicles derived from platelet-rich plasma in tissue repair and regeneration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Pietro GentilePlastic and Reconstructive Surgery, Surgical Science Department, University of Rome "Tor Vergata", 00179 Rome, Italy.ORCID 0000-0003-3123-3977
Claudio CalabreseSan Rossore Clinic, Breast Unit Department, 56122 Pisa, Italy.
Barbara De AngelisPlastic and Reconstructive Surgery, Surgical Science Department, University of Rome "Tor Vergata", 00179 Rome, Italy.
Laura DionisiDionisi Law Firm, 00133 Rome, Italy.
Jacopo PizzicannellaSs. Annunziata Hospital, ASL02 Lanciano-Vasto Chieti, 66100 Chieti, Italy.
Ashutosh KothariHead of Breast Surgery Unit, Guy's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Domenico De FazioInstitute of Plastic Surgery, Galeazzi Hospital, 20122 Milan, Italy.
Simone GarcovichInstitute of Dermatology, Fondazione Policlinico Gemelli IRCSS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
University of Rome Tor Vergata · ITGuy's Hospital · GBIstituto Ortopedico Galeazzi · ITOspedale SS. Annunziata · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous therapies using platelet-rich plasma (PRP) need meticulous preparation-currently, no standardised preparation technique exists. Processing Quantitative Standards (PQSs) define manufacturing quantitative variables (such as time, volume and pressure). Processing Qualitative Standards (PQLSs) define the quality of the materials and methods of manufacturing. The aim of this review is to use existing PQSs and PQLs to report the in vivo/in vitro results obtained by using different Kits, that utilise different procedures (classified as Closed-Technique and Opened-Technique) to isolate autologous human activated (AA-PRP) or non-activated PRP (A-PRP). PQSs included the volumes of blood collected as well as the reagents used, the time/gravity of centrifugation, and the duration, temperature and tilt level/speed of centrifugation. PQLSs included the use of Calcium Chloride CaCl

Indexed as

Surgery, PlasticWound HealingFibrinHairHumansLeukocytesPlatelet-Rich PlasmaFibrinactivated PRPA-PRPautologous platelet-rich plasmanon-activated PRPplatelet-rich plasmaPRPPRP kitPRP proceduresregenerative plastic surgery

Identifiers

PMID31936605
PMCPMC7014364
OpenAlexW3000147288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.