ReviewNutrients2020
Assessment of Malnutrition, Sarcopenia and Frailty in Patients with Cirrhosis: Which Tools Should We Use in Clinical Practice?
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06079021 (COOLEY- Study), which is not on this map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- The global leadership initiative on malnutrition criteria for the diagnosis of malnutrition in patients with chronic liver diseases: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Which vertebral level should be used to calculate sarcopenia in covid-19 patients? A systematic review and meta-analysis.Clinical nutrition ESPEN · 2023Pooled it
- Effects of Branched-Chain Amino Acids on Parameters Evaluating Sarcopenia in Liver Cirrhosis: Systematic Review and Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- Feasibility of Early Oral Nutritional Supplementation After Liver Transplantation: A Randomized Pilot Study.Clinical transplantation · 2026Trial
- Strength training intervention with creatine/whey protein supplementation vs placebo on frailty in older adults with cirrhosis (STRIVE): A Randomized Controlled Trial.Research square · 2026Article
- Sarcopenia is associated with poor swallowing outcomes after resection and free flap reconstruction for oral cancer.Oral oncology reports · 2026Article
- Malnutrition criteria and computed tomography-measured psoas muscle indices in adult liver transplant recipients.Clinical nutrition ESPEN · 2026Article
- Systematic Nutritional Clinical Assessment (SyNCA): Instrument Development, Delphi Protocol for Content, and Semantic Validation.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Article
- Effects of caffeine supplementation on lipid profile and handgrip strength in cirrhotic patients: a randomized, placebo- controlled, clinical trial.BMC nutrition · 2025Article
- Frailty as a predictor of mortality in lung cancer survivors: evidence from a nationally representative cohort NHIS 1997-2018.Scientific reports · 2025Article
- Review
- Review
- Sina Score as a New Machine Learning-Derived Online Prediction Model of Mortality for Cirrhotic Patients Awaiting Liver Transplantation: A Prospective Cohort Study.Journal of clinical medicine · 2025Article
- Incidence and risk factors for recurrence of incisional hernia repair after liver transplantation: a retrospective cohort study.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Evaluation of nutritional parameters that may be associated with survival in patients with locally advanced non-small cell lung carcinoma receiving definitive concurrent chemoradiotherapy: retrospective study conducted in a tertiary pulmonary hospital.Japanese journal of radiology · 2025Article
- A Comparative Study of Dietary Intake, Nutritional Status, and Frailty in Outpatients and Inpatients with Liver Cirrhosis.Nutrients · 2025Observational
- Do Child-Turcotte-Pugh and nutritional assessments predict survival in cirrhosis: A longitudinal study.World journal of hepatology · 2025Article
- Dysgeusia in MASLD-related advanced chronic liver disease (ACLD): a silent driver towards the "Bermuda" triangle of malnutrition-sarcopenia-frailty severely affecting prognosis.Nutrition journal · 2025Review
- The impact of chronic diseases and lifestyle on sarcopenia risk in older adults: a population-based longitudinal study.Frontiers in medicine · 2025Article
- Imaging-based assessment of muscles and malnutrition predict prognosis in patients with primary hepatocellular carcinoma.PloS one · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malnutrition is a common comorbidity in patients with cirrhosis. Its prognostic value is indisputable as it greatly affects the evolution of liver diseases. It has a major impact on both morbi-mortality before and after liver transplantation. Being now integrated in the definition of malnutrition and recognized as a new entity in the international classification of diseases, physicians have taken great interest in sarcopenia. Its negative consequences on the fate of patients with cirrhosis are well-demonstrated. The concept of frailty has recently been enlarged to chronic liver diseases as symptoms of impaired global physical functioning. In this article, we will discuss the definitions of malnutrition and emphasize its links with sarcopenia and frailty. We will show the relevance of frailty and sarcopenia in the course of liver diseases. The emerging role of muscle depletion on the cardiorespiratory system will also be highlighted. The importance of body composition will be demonstrated and the main tools reviewed. Finally, we adapted the definition of malnutrition to patients with cirrhosis based on the assessment of sarcopenia together with reduced food intakes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.