ReviewPolymers2020
Recent Advances in Natural Gum-Based Biomaterials for Tissue Engineering and Regenerative Medicine: A Review.
Review in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bibliometric analysis of research trends and emerging insights of osteoarthritis and chondrocyte hypertrophy.Frontiers in surgery · 2025Pooled it
- Fabrication of Zinc Oxide Nanoparticles Encapsulated Locust Bean Gum for Wound Healing: In Vitro/In Vivo and Molecular Docking Approach.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Natural Polymers in Tissue Engineering and Regeneration: Material-Cell Mechanotransduction, Biofabrication Strategies, and Clinical Translation.Biomedicines · 2026Review
- Eco-Friendly Bioinspired Synthesis and Environmental Applications of Zinc Oxide Nanoparticles Mediated by Natural Polysaccharide Gums: A Sustainable Approach to Nanomaterials Fabrication.Nanomaterials (Basel, Switzerland) · 2026Review
- Balancing Strength and Cell Viability in Gelatin Methacrylate/Gellan Gum Bioink Formulations.ACS omega · 2026Article
- 3D Printing with Tragacanth-Gum-Based Bioinks: A New Frontier in Bioprinting Materials.Gels (Basel, Switzerland) · 2026Review
- Functionality Enhancement of Pullulan-Based Composites for Food Packaging Applications.Comprehensive reviews in food science and food safety · 2026Review
- Sodium alginate-encapsulated Colchicum nanoparticles attenuate TNF-α and NF-κB signaling in macrophages: A novel therapeutic strategy for rheumatoid arthritis.Inflammopharmacology · 2026Article
- Physicochemical Properties, Drug Delivery, and Tissue Engineering Applications of Neem Gum and Its Derivatives: A Comprehensive Review.Mini reviews in medicinal chemistry · 2026Review
- Plant-Based Polysaccharide Gums as Sustainable Bio-Polymers: Focus on Tragacanth Gum and Its Emerging Applications.Polymers · 2025Review
- Biocompatible and antibacterial co-electrospun tragacanth gum and polyaniline nanofibers for skin tissue engineering.Scientific reports · 2025Article
- Evolution in Bone Tissue Regeneration: From Grafts to Innovative Biomaterials.International journal of molecular sciences · 2025Review
- Evaluation of High-Temperature Sterilization Processes: Their Influence on the Mechanical Integrity of Additively Manufactured Polymeric Biomaterials.Materials (Basel, Switzerland) · 2025Article
- Review
- Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways.Inflammopharmacology · 2025Review
- Revolutionizing wild silk fibers: Ultrasound enhances structure, properties, and regenerability of protein biomaterials in ionic liquids.Ultrasonics sonochemistry · 2024Article
- Biopolymeric Insulin Membranes for Antimicrobial, Antioxidant, and Wound Healing Applications.Pharmaceutics · 2024Article
- Exploring gellan gum-based hydrogels for regenerating human embryonic stem cells in age-related macular degeneration therapy: A literature review.Regenerative therapy · 2024Review
- Review
- Embedded 3D bioprinting - An emerging strategy to fabricate biomimetic & large vascularized tissue constructs.Bioactive materials · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The engineering of tissues under a three-dimensional (3D) microenvironment is a great challenge and needs a suitable supporting biomaterial-based scaffold that may facilitate cell attachment, spreading, proliferation, migration, and differentiation for proper tissue regeneration or organ reconstruction. Polysaccharides as natural polymers promise great potential in the preparation of a three-dimensional artificial extracellular matrix (ECM) (i.e., hydrogel) via various processing methods and conditions. Natural polymers, especially gums, based upon hydrogel systems, provide similarities largely with the native ECM and excellent biological response. Here, we review the origin and physico-chemical characteristics of potentially used natural gums. In addition, various forms of scaffolds (e.g., nanofibrous, 3D printed-constructs) based on gums and their efficacy in 3D cell culture and various tissue regenerations such as bone, osteoarthritis and cartilage, skin/wound, retinal, neural, and other tissues are discussed. Finally, the advantages and limitations of natural gums are precisely described for future perspectives in tissue engineering and regenerative medicine in the concluding remarks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.