ArticleNanomaterials (Basel, Switzerland)2020
Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE.
Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 63 citations in OpenAlex.
- Advanced Electrochemical Sensors for Rapid and Sensitive Monitoring of Tryptophan and Tryptamine in Clinical Diagnostics.Biosensors · 2025Review
- Ultra-sensitive electrochemical sensor based on molecularly imprinted polydopamine grafted with MWCNT-COOH for tryptophan detection.Mikrochimica acta · 2025Article
- Highly Sensitive and Selective Detection of L-Tryptophan by ECL Using Boron-Doped Diamond Electrodes.Sensors (Basel, Switzerland) · 2024Article
- Nitrogen Defect-Rich Graphitic Carbon Nitride for Highly Sensitive Voltammetric Determination of Tryptophan.ACS omega · 2023Article
- Zirconium Molybdate Nanocomposites' Sensing Platform for the Sensitive and Selective Electrochemical Detection of Adefovir.Molecules (Basel, Switzerland) · 2022Article
- Review
- Investigation of L-Tryptophan Electrochemical Oxidation with a Graphene-Modified Electrode.Biosensors · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper, an electrochemical method for the measurement of tryptophan (Trp) was developed based on a glassy carbon electrode modified with polyvinylpyrrolidonefunctionalized graphene (PVP-GR)/glassy carbon electrode (GCE). In 0.1 M phosphate buffer solution (PBS, pH = 2.2), compared with bare GCE, PVP/GCE, and GR/GCE, the oxidation peak current of Trp increased dramatically at PVP-GR/GCE. The oxidation mechanism of Trp on the PVP-GR/GCE was discussed and the experimental conditions were optimized. Under the best experimental conditions, the oxidation peak current of Trp was proportional to its concentration in the range of 0.06 µM-10.0 µM and 10.0-100.0 µM, and the limit of detection (LOD) was 0.01 µM (S/N = 3). The target modified electrode with excellent repeatability, stability and selectivity, was successfully applied to detectTrp in drugs and biological samples.
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