Evidence map›Paper›PMID 31936460›Full record

ArticleCancers2020

Circulating Tumor Cells as a Marker of Disseminated Disease in Patients with Newly Diagnosed High-Risk Prostate Cancer.

Wojciech A Cieślikowski, Joanna Budna-Tukan, Monika Świerczewska, Agnieszka Ida, Michał Hrab, Agnieszka Jankowiak, Martine Mazel, Michał Nowicki, Piotr Milecki, Klaus Pantel and 3 more

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Bioprinted research models of urological malignancy.Exploration (Beijing, China) · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
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  16. Review
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  18. Article
  19. Circulating tumor cells: biology and clinical significance.Signal transduction and targeted therapy · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wojciech A CieślikowskiDepartment of Urology, Poznan University of Medical Sciences, 61-285 Poznan, Poland.ORCID 0000-0002-9257-6888
Joanna Budna-TukanDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.ORCID 0000-0001-9285-5417
Monika ŚwierczewskaDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.ORCID 0000-0001-6483-9524
Agnieszka IdaDepartment of Urology, Poznan University of Medical Sciences, 61-285 Poznan, Poland.
Michał HrabDepartment of Urology, Poznan University of Medical Sciences, 61-285 Poznan, Poland.
Agnieszka JankowiakDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Martine MazelLaboratory of Rare Human Circulating Cells, University Medical Center, 34093 Montpellier CEDEX 5, France.ORCID 0000-0002-0269-5243
Michał NowickiDepartment of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Piotr MileckiDepartment of Electroradiology, Poznan University of Medical Sciences, 61-868 Poznan, Poland.
Klaus PantelDepartment of Tumor Biology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-5736-2772
Catherine Alix-PanabièresLaboratory of Rare Human Circulating Cells, University Medical Center, 34093 Montpellier CEDEX 5, France.ORCID 0000-0002-6401-2903
Maciej ZabelDivision of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Andrzej AntczakDepartment of Urology, Poznan University of Medical Sciences, 61-285 Poznan, Poland.

Funding

FEDER -French National Institute of Cancer as well as the Innovative Medicines Initiative Joint Undertaking n°115749Region Languedoc-Roussillon GEPETOSThe National Centre for Research and Development (Poland) 01/2018The National Centre for Research and Development (Poland) 03/2013
6 · The paper itself

Abstract

The aim of this study was to investigate whether the enumeration of circulating tumor cells (CTCs) in blood can differentiate between true localized and metastatic prostate cancer. A cross-sectional study of 104 prostate cancer patients with newly diagnosed high-risk prostate cancer was conducted. In total, 19 patients presented metastatic disease and 85 were diagnosed with localized disease. Analyses included intergroup comparison of CTC counts, determined using the CellSearch

Indexed as

circulating tumor cells (CTCs)early detectionmetastasesprostate cancerradiotherapy

Identifiers

PMID31936460
PMCPMC7017349

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.