Evidence map›Paper›PMID 31936295›Full record

ArticleInternational journal of environmental research and public health2020

Influence of Ambient Air Pollution on Rheumatoid Arthritis Disease Activity Score Index.

Ahmad Alsaber, Jiazhu Pan, Adeeba Al-Herz, Dhary S Alkandary, Adeeba Al-Hurban, Parul Setiya, On Behalf Of The Krrd Group

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Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  10. Epidemiology and Risk Factors for Rheumatoid Arthritis Development.Mediterranean journal of rheumatology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmad AlsaberDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow G1 1XH, UK.ORCID 0000-0001-9478-0404
Jiazhu PanDepartment of Mathematics and Statistics, University of Strathclyde, Glasgow G1 1XH, UK.
Adeeba Al-HerzDepartment of Rheumatology, Al-Amiri Hospital, P.O. Box 4077, Safat 13041, Kuwait.
Dhary S AlkandaryDepartment of Earth and Environmental Sciences, Kuwait University, P.O. Box 25944, Safat 1320, Kuwait.
Adeeba Al-HurbanDepartment of Earth and Environmental Sciences, Kuwait University, P.O. Box 25944, Safat 1320, Kuwait.
Parul SetiyaDepartment of Agrometerology, Govind Ballabh Pant University of Agriculture & Technology, Pantnagar, Uttarakhand 263145, India.
On Behalf Of The Krrd Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune of an unknown etiology. Air pollution has been proposed as one of the possible risk factors associated with disease activity, although has not been extensively studied. In this study, we measured the relationship between exposure to air pollutants and RA activity. Data on RA patients were extracted from the Kuwait Registry for Rheumatic Diseases (KRRD). Disease activity was measured using disease activity score with 28 examined joints (DAS-28) and the Clinical Disease Activity Index (CDAI) during their hospital visits from 2013 to 2017. Air pollution was assessed using air pollution components (PM 10 , NO 2 , SO 2 , O 3 , and CO). Air pollution data were obtained from Kuwait Environmental Public Authority (K-EPA) from six different air quality-monitoring stations during the same period. Multiple imputations by the chained equations (MICE) algorithm were applied to estimate missing air pollution data. Patients data were linked with air pollution data according to date and patient governorate address. Descriptive statistics, correlation analysis, and linear regression techniques were employed using STATA software. In total, 1651 RA patients with 9875 follow-up visits were studied. We detected an increased risk of RA using DAS-28 in participants exposed to SO 2 and NO 2 with β = 0 . 003 (95% CI: 0.0004-0.005, p < 0 . 01 ) and β = 0 . 003 (95% CI: 0.002-0.005, p < 0 . 01 ), respectively, but not to PM 10 , O 3 , and CO concentrations. Conclusively, we observed a strong association between air pollution with RA disease activity. This study suggests air pollution as a risk factor for RA and recommends further measures to be taken by the authorities to control this health problem.

Indexed as

Air PollutionArthritis, RheumatoidFemaleHumansKuwaitLinear ModelsMaleRisk Factorsair pollutionAQICDAIDAS-28KRRDKuwaitMiddle EastRA registryrheumatoid arthritis

Identifiers

PMID31936295
PMCPMC7013841

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.