Evidence map›Paper›PMID 31936161›Full record

ArticleMolecules (Basel, Switzerland)2020

A New Look into the Mode of Action of Metal-Based Anticancer Drugs.

M Paula M Marques, Ana L M Batista de Carvalho, Adriana P Mamede, Asha Dopplapudi, Svemir Rudić, Madhusudan Tyagi, Victoria Garcia Sakai, Luís A E Batista de Carvalho

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Chemotherapeutic Activity of Imidazolium-Supported Pd(II)Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. PdBiomedicines · 2022
    Article
  8. Article
  9. Article
  10. Functionalized azobenzene platinum(II) complexes as putative anticancer compounds.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

M Paula M MarquesUnidade de I&D Química-Física Molecular, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal.
Ana L M Batista de CarvalhoUnidade de I&D Química-Física Molecular, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal.
Adriana P MamedeUnidade de I&D Química-Física Molecular, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal.
Asha DopplapudiISIS Facility, STFC Rutherford Appleton Laboratory, Chilton, Didcot OX11 0QX, UK.
Svemir RudićISIS Facility, STFC Rutherford Appleton Laboratory, Chilton, Didcot OX11 0QX, UK.
Madhusudan TyagiNIST Center for Neutron Research, Gaithersburg, Maryland, MD 20899, USA.
Victoria Garcia SakaiISIS Facility, STFC Rutherford Appleton Laboratory, Chilton, Didcot OX11 0QX, UK.
Luís A E Batista de CarvalhoUnidade de I&D Química-Física Molecular, Department of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal.
University of Coimbra · PTRutherford Appleton Laboratory · GBNIST Center for Neutron Research · US

Funding

European Regional Development Fund Centro-01-0145-FEDER-029956European Regional Development Fund POCI-01-0145-FEDER-0016786Fundação para a Ciência e a Tecnologia UID/Multi/00070/2019
6 · The paper itself

Abstract

The mode of action of Pt- and Pd-based anticancer agents (cisplatin and Pd

Indexed as

Antineoplastic AgentsCisplatinDNAElasticityMetalsNeutron DiffractionNeutronsNucleic Acid ConformationPalladiumSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanSpermineWaterAntineoplastic AgentsCisplatinDNAMetalsPalladiumSpermineWaterDNAFTIRhydration waterneutron scattering techniquespalladium anticancer drugRaman

Identifiers

PMID31936161
PMCPMC7024343
OpenAlexW2999491485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.