Evidence map›Paper›PMID 31936129›Full record

ArticleCells2020

Delineating the Molecular Basis of the Calmodulin‒bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry-Evidence for a Novel CaM Binding Motif in bMunc13-2.

Christine Piotrowski, Rocco Moretti, Christian H Ihling, André Haedicke, Thomas Liepold, Noa Lipstein, Jens Meiler, Olaf Jahn, Andrea Sinz

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Protein Structure Prediction with Mass Spectrometry Data.Annual review of physical chemistry · 2022
    Review
  6. Article
  7. Review
  8. Munc13-1 is a CaNeuron · 2021
    Article
  9. (M)Unc13s in Active Zone Diversity: AFrontiers in synaptic neuroscience · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Christine PiotrowskiDepartment of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, D-06120 Halle/Saale, Germany.
Rocco MorettiCenter for Structural Biology, Department of Chemistry, Vanderbilt University, Nashville, TN 37221, USA.
Christian H IhlingDepartment of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, D-06120 Halle/Saale, Germany.
André HaedickeBiophysical Chemistry, Institute of Chemistry, Martin Luther University Halle-Wittenberg, D-06120 Halle/Saale, Germany.
Thomas LiepoldProteomics Group, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.
Noa LipsteinDepartment of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.
Jens MeilerCenter for Structural Biology, Department of Chemistry, Vanderbilt University, Nashville, TN 37221, USA.
Olaf JahnProteomics Group, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany.
Andrea SinzDepartment of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, D-06120 Halle/Saale, Germany.
Martin Luther University Halle-Wittenberg · DEMax Planck Institute of Experimental Medicine · DEVanderbilt University · US

Funding

Membrane Protein Structure Elucidation from sparse NMR data (KAMP)R01GM080403 · NIGMS · VANDERBILT UNIVERSITY · PI MEILER, JENS · 2007 to 2019
$3.0M
NIGMS NIH HHS R01 GM080403
6 · The paper itself

Abstract

Exploring the interactions between the Ca

Indexed as

Mass SpectrometryAmino Acid MotifsAmino Acid SequenceAnimalsBinding SitesCalmodulinCattleCross-Linking ReagentsHydrophobic and Hydrophilic InteractionsModels, MolecularNerve Tissue ProteinsProtein BindingProtein DomainsRatsSwineCalmodulinCross-Linking ReagentsNerve Tissue ProteinsUnc13b protein, ratcalmodulincross-linkingmass spectrometryMunc13protein‒protein interaction

Identifiers

PMID31936129
PMCPMC7017353
OpenAlexW3000559830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.