Evidence map›Paper›PMID 31935991›Full record

ReviewInternational journal of environmental research and public health2020

A Review of Respiratory Anatomical Development, Air Flow Characterization and Particle Deposition.

Mohammad S Islam, Gunther Paul, Hui X Ong, Paul M Young, Y T Gu, Suvash C Saha

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 117 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Heat Wave and Bushfire Meteorology in New South Wales, Australia: Air Quality and Health Impacts.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Airborne transmission of respiratory viruses.Science (New York, N.Y.) · 2021
    Review
  16. Article
  17. Article
  18. Polydisperse Aerosol Transport and Deposition in Upper Airways of Age-Specific Lung.International journal of environmental research and public health · 2021
    Article
  19. SARS CoV-2 aerosol: How far it can travel to the lower airways?Physics of fluids (Woodbury, N.Y. : 1994) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mohammad S IslamSchool of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, NSW 2007, Australia.ORCID 0000-0001-6264-3886
Gunther PaulAustralian Institute of Tropical Health and Medicine, James Cook University, Mackay, QLD 4741, Australia.ORCID 0000-0002-1880-9161
Hui X OngRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, 431 Glebe Point Road, Glebe, NSW 2037, Australia.ORCID 0000-0002-2882-1551
Paul M YoungRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, 431 Glebe Point Road, Glebe, NSW 2037, Australia.
Y T GuSchool of Chemistry, Physics & Mechanical Engineering, Queensland University of Technology 2 George Street, GPO Box 2434, Brisbane, QLD 4001, Australia.
Suvash C SahaSchool of Mechanical and Mechatronic Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Ultimo, NSW 2007, Australia.ORCID 0000-0002-9962-8919
The University of Sydney · AUUniversity of Technology Sydney · AUAustralian Institute of Tropical Health and Medicine · AUQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The understanding of complex inhalation and transport processes of pollutant particles through the human respiratory system is important for investigations into dosimetry and respiratory health effects in various settings, such as environmental or occupational health. The studies over the last few decades for micro- and nanoparticle transport and deposition have advanced the understanding of drug-aerosol impacts in the mouth-throat and the upper airways. However, most of the Lagrangian and Eulerian studies have utilized the non-realistic symmetric anatomical model for airflow and particle deposition predictions. Recent improvements to visualization techniques using high-resolution computed tomography (CT) data and the resultant development of three dimensional (3-D) anatomical models support the realistic representation of lung geometry. Yet, the selection of different modelling approaches to analyze the transitional flow behavior and the use of different inlet and outlet conditions provide a dissimilar prediction of particle deposition in the human lung. Moreover, incorporation of relevant physical and appropriate boundary conditions are important factors to consider for the more accurate prediction of transitional flow and particle transport in human lung. This review critically appraises currently available literature on airflow and particle transport mechanism in the lungs, as well as numerical simulations with the aim to explore processes involved. Numerical studies found that both the Euler-Lagrange (E-L) and Euler-Euler methods do not influence nanoparticle (particle diameter ≤50 nm) deposition patterns at a flow rate ≤25 L/min. Furthermore, numerical studies demonstrated that turbulence dispersion does not significantly affect nanoparticle deposition patterns. This critical review aims to develop the field and increase the state-of-the-art in human lung modelling.

Indexed as

Air PollutantsParticle SizePhysical PhenomenaRespirationAdultAgedAged, 80 and overBiological TransportComputer SimulationFemaleHumansLungMaleMiddle AgedModels, AnatomicModels, BiologicalAir PollutantsairflowEuler-Euler approachEuler-Lagrange methodparticle depositionparticle-particle interactionparticle transport

Identifiers

PMID31935991
PMCPMC7014067
OpenAlexW2997199111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.