ArticleMarine drugs2020
Ectoine from Bacterial and Algal Origin Is a Compatible Solute in Microalgae.
Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 75 citations in OpenAlex.
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- Metabolic partitioning between photosynthesis and osmotrophy in Collodaria photosymbiotic holobionts.Nature communications · 2026Article
- Characterization of phytoplankton-excreted metabolites mediating carbon flux through the surface ocean.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Marine BacteriumJournal of natural products · 2026Article
- Multi-omics uncovers nutrient stress-driven interactions in a syntheticISME communications · 2026Article
- Identifying potential keystone bacterial species within the phycosphere of marine algae and unveiling their metabolic characteristics.Marine life science & technology · 2025Article
- Metabolic interdependence and rewiring in radiolaria-microalgae photosymbioses.The ISME journal · 2025Article
- Life in the brine of Lunenburg, Germany: unveiling microorganisms associated with Zechstein salt deposits.Frontiers in microbiology · 2025Article
- Bacterial and fungal composition and exometabolites control the development and persistence of soil water repellency.ISME communications · 2025Article
- How to fight acute sun damage? Current skin care strategies.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Unlocking the genomic potential of Red Sea coral probiotics.Scientific reports · 2024Article
- Improvement in Salt Tolerance Ability ofBiology · 2024Article
- Diatom-Bacteria Interactions in the Marine Environment: Complexity, Heterogeneity, and Potential for Biotechnological Applications.Microorganisms · 2023Review
- Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation.Marine drugs · 2023Article
- Microbial metabolomic responses to changes in temperature and salinity along the western Antarctic Peninsula.The ISME journal · 2023Article
- MariClus: Your One-Stop Platform for Information on Marine Natural Products, Their Gene Clusters and Producing Organisms.Marine drugs · 2023Article
- Metabolic engineering of Halomonas campaniensis strain XH26 to remove competing pathways to enhance ectoine production.Scientific reports · 2023Article
- Insights into the potential for mutualistic and harmful host-microbe interactions affecting brown alga freshwater acclimation.Molecular ecology · 2023Article
- Antioxidants in Sunscreens: Which and What For?Antioxidants (Basel, Switzerland) · 2023Article
- Improved salt tolerance ofFrontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Osmoregulation in phytoplankton is attributed to several highly polar low-molecular-weight metabolites. A widely accepted model considers dimethylsulfoniopropionate (DMSP) as the most important and abundant osmotically active metabolite. Using an optimized procedure for the extraction and detection of highly polar metabolites, we expand the group of phytoplankton osmolytes by identifying ectoine in several microalgae. Ectoine is known as a bacterial compatible solute, but, to the best of our knowledge, was never considered as a phytoplankton-derived product. Given the ability of microalgae to take up zwitterions, such as DMSP, we tested the hypothesis that the algal ectoine is derived from associated bacteria. We therefore analyzed methanol extracts of xenic and axenic cultures of two different species of microalgae and could detect elevated concentrations of ectoine in those that harbor associated bacteria. However, also microalgae without an associated microbiome contain ectoine in smaller amounts, pointing towards a dual origin of this metabolite in the algae from their own biosynthesis as well as from uptake. We also tested the role of ectoine in the osmoadaptation of microalgae. In the model diatoms Thalassiosira weissflogii and Phaeodactylum tricornutum, elevated amounts of ectoine were found when cultivated in seawater with salinities of 50 PSU compared to the standard culture conditions of 35 PSU. Therefore, we add ectoine to the family of osmoadaptive metabolites in phytoplankton and prove a new, potentially synergistic metabolic interplay of bacteria and algae.
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