Evidence map›Paper›PMID 31935897›Full record

ArticlePolymers2020

Development of Water-Compatible Molecularly Imprinted Polymers Based on Functionalized β-Cyclodextrin for Controlled Release of Atropine.

Yahui He, Shaomei Zeng, A M Abd El-Aty, Ahmet Hacımüftüoğlu, Woldemariam Kalekristos Yohannes, Majid Khan, Yongxin She

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Yahui HeChina-Canada Joint Lab of Food Nutrition and Health (Beijing), School of Food and Health, Beijing Technology &Business University, Beijing 100048, China.
Shaomei ZengInstitute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
A M Abd El-AtyState Key Laboratory of Biobased Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan 250353, China.ORCID 0000-0001-6596-7907
Ahmet HacımüftüoğluDepartment of Medical Pharmacology, Medical Faculty, Ataturk University, 25240 Erzurum, Turkey.
Woldemariam Kalekristos YohannesChina-Canada Joint Lab of Food Nutrition and Health (Beijing), School of Food and Health, Beijing Technology &Business University, Beijing 100048, China.ORCID 0000-0002-8318-230X
Majid KhanChina-Canada Joint Lab of Food Nutrition and Health (Beijing), School of Food and Health, Beijing Technology &Business University, Beijing 100048, China.ORCID 0000-0001-9768-8224
Yongxin SheInstitute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Beijing Technology and Business University · CNChinese Academy of Agricultural Sciences · CNAtatürk University · TRCairo University · EG

Funding

National Natural Science Foundation of China No. 31772071
6 · The paper itself

Abstract

Herein, a novel method for molecularly imprinted polymers (MIPs) using methacrylic acid functionalized beta-cyclodextrin (MAA-β-CD) monomer is presented, which was designed as a potential water-compatible composite for the controlled release of atropine (ATP). The molecularly imprinted microspheres with pH-sensitive characteristics were fabricated using thermally-initiated precipitation polymerization, employing ATP as a template molecule. The effects of different compounds and concentrations of cross-linking agents were systematically investigated. Uniform microspheres were obtained when the ratio between ATP, MAA-β-CD, and trimethylolpropane trimethacrylate (TRIM) was 1:4:20 (mol/mol/mol) in polymerization system. The ATP loading equilibrium data was best suited to the Freundlich and Langmuir isotherm models. The

Indexed as

Atropinecontrolled releasemolecularly imprinted polymerswater-compatibleβ-cyclodextrin

Identifiers

PMID31935897
PMCPMC7022701
OpenAlexW2997203045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.