Evidence map›Paper›PMID 31935837›Full record

ArticlePharmaceutics2020

Poly(Ethylene Glycol) Crosslinked Multi-Armed Poly(l-Lysine) with Encapsulating Capacity and Antimicrobial Activity for the Potential Treatment of Infection-Involved Multifactorial Diseases.

Chao Lu, Ting Wen, Maochao Zheng, Daojun Liu, Guilan Quan, Xin Pan, Chuanbin Wu

Abstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chao LuSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.ORCID 0000-0002-2118-8888
Ting WenSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Maochao ZhengDepartment of chemistry, Shantou University Medical College, Shantou 515041, China.
Daojun LiuDepartment of chemistry, Shantou University Medical College, Shantou 515041, China.
Guilan QuanSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.ORCID 0000-0002-6106-592X
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Chuanbin WuSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.

Funding

China Postdoctoral Science Foundation No. 2018M633259National Natural Science Foundation of China No. 81803467
6 · The paper itself

Abstract

With the development of modern medical technology, common diseases usually can be treated by traditional medicines and their formulation, while diseases with multiple etiologies still remain a great challenge in clinic. Nanoformulation was widely explored to address this problem. However, due to limited drug loading space of nanocarriers, co-delivery strategy usually fails to achieve sufficient loading of multiple drugs simultaneously. In this research, we explored the potential of poly(ethylene glycol) (PEG) crosslinked alternating copolymers MPLL-

Indexed as

antimicrobial polymerdrug delivery systemsmultifactorial diseasespolyion complex micellesshell crosslinked micelles

Identifiers

PMID31935837
PMCPMC7022689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.