Evidence map›Paper›PMID 31934859›Full record

ArticleeLife2020

Ankyrin-G mediates targeting of both Na

Hua-Qian Yang, Marta Pérez-Hernández, Jose Sanchez-Alonso, Andriy Shevchuk, Julia Gorelik, Eli Rothenberg, Mario Delmar, William A Coetzee

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. A Correlative SICM-OPM Platform for Surface and Volumetric Imaging in Live Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  6. The cardioprotective role of sirtuins is mediated in part by regulating KAmerican journal of physiology. Cell physiology · 2023
    Article
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  14. Subcellular trafficking and endocytic recycling of KAmerican journal of physiology. Cell physiology · 2022
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Palmitoylation of the KProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hua-Qian YangPediatrics, NYU School of Medicine, New York, United States.ORCID 0000-0002-9402-6222
Marta Pérez-HernándezMedicine, NYU School of Medicine, New York, United States.
Jose Sanchez-AlonsoNational Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, United Kingdom.
Andriy ShevchukDepartment of Medicine, Imperial College London, London, United Kingdom.
Julia GorelikNational Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-1148-9158
Eli RothenbergBiochemistry and Molecular Pharmacology, NYU School of Medicine, New York, United States.ORCID 0000-0002-1382-1380
Mario DelmarMedicine, NYU School of Medicine, New York, United States.
William A CoetzeePediatrics, NYU School of Medicine, New York, United States.ORCID 0000-0003-1522-8326
New York University · USLung Institute · USImperial College London · GB

Funding

Role of PKP2 in epicardial structure and functionR01HL136179 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2017 to 2020
$3.1M
Roles of Endothelial and Smooth Muscle KATP Channels in Myocardial Ischemic InjuryR01HL146514 · NHLBI · LSU HEALTH SCIENCES CENTER · PI COETZEE, WILLIAM A, LEFER, DAVID JOSEPH · 2020 to 2023
$3.0M
Exploration of Arrhythmogenic Triggers and Substrates in Heart FailureR01HL126802 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI EFIMOV, IGOR R, GORELIK, JULIA · 2016 to 2019
$2.8M
KATP Channel Trafficking and CardioprotectionR01HL126905 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COETZEE, WILLIAM A · 2015 to 2018
$2.7M
Role of desmosomes in cardiac electrical functionR01HL134328 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2016 to 2019
$2.6M
The sodium channel ecosystem in the adult ventricular myocyteR01HL145911 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO · 2019 to 2021
$1.5M
Biotechnology and Biological Sciences Research Council BB/M022080British Heart Foundation RG/17/13/33173NHLBI NIH HHS R01 HL126802NHLBI NIH HHS R01 HL126905NHLBI NIH HHS R01 HL134328NHLBI NIH HHS R01 HL136179NHLBI NIH HHS R01 HL145911NHLBI NIH HHS R01 HL146514NIH HHS HL126802NIH HHS HL126905NIH HHS HL134328NIH HHS HL136179NIH HHS HL145911NIH HHS HL146514
6 · The paper itself

Abstract

We investigated targeting mechanisms of Na

Indexed as

Gene Expression RegulationAnimalsAnkyrinsBinding SitesBiotinylationHEK293 CellsHumansKcnj11 ChannelMutagenesisMyocardiumMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelPatch-Clamp TechniquesPotassium Channels, Inwardly RectifyingRatsAnk3 protein, ratAnkyrinsKcnj11 ChannelNAV1.5 Voltage-Gated Sodium ChannelPotassium Channels, Inwardly RectifyingScn5a protein, ratATP-sensitive K+ channelchannel interactionshearthuman biologyintercalated diskmedicineNa+ channelrat

Identifiers

PMID31934859
PMCPMC7299345
OpenAlexW2999933258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.