Evidence map›Paper›PMID 31934858›Full record

ArticleeLife2020

Prickle isoforms determine handedness of helical morphogenesis.

Bomsoo Cho, Song Song, Jeffrey D Axelrod

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bomsoo ChoDepartment of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID 0000-0001-8970-9160
Song SongDepartment of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID 0000-0002-4587-8592
Jeffrey D AxelrodDepartment of Pathology, Stanford University School of Medicine, Stanford, United States.ORCID 0000-0001-6094-7392
Stanford University · US

Funding

Planar cell polarity mechanisms and systems architectureR35GM131914 · NIGMS · STANFORD UNIVERSITY · PI Jeffrey D. Axelrod · 2019 to 2026
$7.4M
Comparative analysis of PCP signaling architectureR01GM097081 · NIGMS · STANFORD UNIVERSITY · PI AXELROD, JEFFREY D. · 2012 to 2019
$2.8M
Signaling mechanisms Controlling Planar Cell PolarityR37GM059823 · NIGMS · STANFORD UNIVERSITY · PI AXELROD, JEFFREY D. · 2014 to 2018
$1.8M
NIGMS NIH HHS R01 GM097081NIGMS NIH HHS R35 GM131914NIGMS NIH HHS R37 GM059823
6 · The paper itself

Abstract

Subcellular asymmetry directed by the planar cell polarity (PCP) signaling pathway orients numerous morphogenetic events in both invertebrates and vertebrates. Here, we describe a morphogenetic movement in which the intertwined socket and shaft cells of the

Indexed as

Gene Expression Regulation, DevelopmentalAllelesAnimalsBody PatterningCell PolarityDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGenotypeLIM Domain ProteinsMorphogenesisMutationProtein IsoformsSignal TransductionWings, AnimalDNA-Binding ProteinsDrosophila ProteinsLIM Domain Proteinspk protein, DrosophilaProtein Isoformsbristle chiralitycell biologyD. melanogasterplanar cell polarityPrickle

Identifiers

PMID31934858
PMCPMC7004564
OpenAlexW3000152181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.