ArticleeLife2020
The bottom-up and top-down processing of faces in the human occipitotemporal cortex.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Mental Imagery Enhances Pain Reduction and Visual Processing in Knee Osteoarthritis Patients: A Comparative Study.Pain research & management · 2025Trial
- Feedforward Processing in Early Visual Cortex Underlies the Ebbinghaus Illusion.Cognitive science · 2026Article
- The representation of facial emotion expands from sensory to prefrontal cortex with development.eLife · 2026Article
- The representation of facial emotion expands from sensory to prefrontal cortex with development.bioRxiv : the preprint server for biology · 2025Article
- Multiarea processing in body patches of the primate inferotemporal cortex implements inverse graphics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Visual hallucinations in Parkinson's disease are associated with deficits in social perception.Journal of Parkinson's disease · 2025Article
- Psychophysical assessment of face perception deficits in adults with amblyopia through top-down and bottom-up visual processing pathways.Frontiers in neuroscience · 2025Article
- Studying perceptual bias in favor of the from-above Necker cube perspective in a goal-directed behavior.Frontiers in psychology · 2023Article
- Positive hysteresis in emotion recognition: Face processing visual regions are involved in perceptual persistence, which mediates interactions between anterior insula and medial prefrontal cortex.Cognitive, affective & behavioral neuroscience · 2022Article
- Revisiting the effective connectivity within the distributed cortical network for face perception.Neuroimage. Reports · 2021Article
- Face-selective responses in combined EEG/MEG recordings with fast periodic visual stimulation (FPVS).NeuroImage · 2021Article
- Global and high-level effects in crowding cannot be predicted by either high-dimensional pooling or target cueing.Journal of vision · 2021Article
- Gestalts at threshold could reveal Gestalts as predictions.Scientific reports · 2021Article
- Perceptual difficulty modulates the direction of information flow in familiar face recognition.NeuroImage · 2021Article
- Children with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces.Autism research : official journal of the International Society for Autism Research · 2021Article
- Clarifying the role of higher-level cortices in resolving perceptual ambiguity using ultra high field fMRI.NeuroImage · 2021Article
- A Cautionary Note on Predicting Social Judgments from Faces with Deep Neural Networks.Affective science · 2021Article
- Special Patterns of Dynamic Brain Networks Discriminate Between Face and Non-face Processing: A Single-Trial EEG Study.Frontiers in neuroscience · 2021Article
- Free-Living Physical Activity Measured With a Wearable Device Is Associated With Larger Hippocampus Volume and Greater Functional Connectivity in Healthy Older Adults: An Observational, Cross-Sectional Study in Northern Portugal.Frontiers in aging neuroscience · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Although face processing has been studied extensively, the dynamics of how face-selective cortical areas are engaged remains unclear. Here, we uncovered the timing of activation in core face-selective regions using functional Magnetic Resonance Imaging and Magnetoencephalography in humans. Processing of normal faces started in the posterior occipital areas and then proceeded to anterior regions. This bottom-up processing sequence was also observed even when internal facial features were misarranged. However, processing of two-tone Mooney faces lacking explicit prototypical facial features engaged top-down projection from the right posterior fusiform face area to right occipital face area. Further, face-specific responses elicited by contextual cues alone emerged simultaneously in the right ventral face-selective regions, suggesting parallel contextual facilitation. Together, our findings chronicle the precise timing of bottom-up, top-down, as well as context-facilitated processing sequences in the occipital-temporal face network, highlighting the importance of the top-down operations especially when faced with incomplete or ambiguous input.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.