Evidence map›Paper›PMID 31934672›Full record

ArticleIndian journal of cardiovascular disease in women WINCARS2018

Cardiac Biomarkers: What Is and What Can Be.

Rachel Jacob, Mahmood Khan

Abstract read
In one paragraph

Article in Indian journal of cardiovascular disease in women WINCARS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Cardiovascular Biomarkers: Tools for Precision Diagnosis and Prognosis.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Article
  14. Cardiac Involvement in Idiopathic Inflammatory Myopathies.Journal of inflammation research · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. Elevated Cardiac Troponin I Level Associated to Cardiac Dysfunction in Burned Patients.Journal of burn care & research : official publication of the American Burn Association · 2024
    Article
  19. Review
  20. Cardiovascular biomarkers: exploring troponin and BNP applications in conditions related to carbon monoxide exposure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel JacobDepartment of Biochemistry, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India.
Mahmood KhanDepartment of Emergency Medicine, Department of Physiology and Cell Biology, Cardiovascular Stem Cell Therapeutics Lab, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, United States.

Funding

Biomimetic cardiac patch capable of rapid angiogenesisR01HL136232 · NHLBI · OHIO STATE UNIVERSITY · PI KHAN, MAHMOOD · 2017 to 2021
$2.8M
NHLBI NIH HHS R01 HL136232
6 · The paper itself

Abstract

Cardiac biomarkers are of great importance in the timely, accurate diagnosis and management of acute coronary syndrome as well as the prognosis. Diagnosis in the golden period is of utmost importance to institute therapy at the earliest and possibly reverse the myocardial damage. Cardiac biomarkers are also a powerful tool for triaging. Among the many biomarkers, the earliest examined were the myocardial enzymes, several myocardial proteins, peptides, and many other molecules. The latest addition to the repertoire is the microRNAs, which are stable molecules detectable in circulation. About four groups are found to be involved in regulation of circulatory system, and some show promise as specific and early markers of acute coronary syndrome and cardiac dysfunction. As in other fields of medicine, personalized precise treatment may be possible with the use of microRNAs. However, as of now, a multipronged approach, involving different markers of which troponins are necessary, seems to be the best way forward.

Indexed as

cardiac biomarkerscardiovascular diseasemicroRNA

Identifiers

PMID31934672
PMCPMC6957084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.