Evidence map›Paper›PMID 31934596›Full record

ArticleEye and vision (London, England)2020

Genetic characterization of Stargardt clinical phenotype in South Indian patients using sanger and targeted sequencing.

Rajendran Kadarkarai Raj, Pankaja Dhoble, Rupa Anjanamurthy, Prakash Chermakani, Manojkumar Kumaran, Bharanidharan Devarajan, Periasamy Sundaresan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Eye and vision (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rajendran Kadarkarai Raj1Department of Genetics, Aravind Medical Research Foundation-Madurai, No.1 Anna Nagar, Madurai, Tamil Nadu 625 020 India.
Pankaja Dhoble2Retina Consultant, Department of Vitreo Retinal services, Aravind Eye Hospital-Pondicherry, Puducherry, India.
Rupa Anjanamurthy3Department of Paediatrics and Adult strabismus, Aravind Eye Hospital-Madurai, Madurai, Tamil Nadu India.
Prakash Chermakani1Department of Genetics, Aravind Medical Research Foundation-Madurai, No.1 Anna Nagar, Madurai, Tamil Nadu 625 020 India.
Manojkumar Kumaran4Department of Bioinformatics, Aravind Medical Research Foundation-Madurai, Madurai, Tamil Nadu India.
Bharanidharan Devarajan4Department of Bioinformatics, Aravind Medical Research Foundation-Madurai, Madurai, Tamil Nadu India.
Periasamy Sundaresan1Department of Genetics, Aravind Medical Research Foundation-Madurai, No.1 Anna Nagar, Madurai, Tamil Nadu 625 020 India.
Madurai Medical College · INAravind Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStargardt disease 1 (STGD1; MIM 248200) is a monogenic form of autosomal recessive genetic disease caused by mutation in

methodsA total of 28 clinically diagnosed Stargardt-like phenotype patients were recruited from south India. Ophthalmic examination of all patients was carefully carried out by a retina specialist based on the stages of fundus imaging and ERG grouping. Genetic analysis of

resultsThis study identified disease-causing mutations in

conclusionThis is the first study describing the genetic association of

Indexed as

ABCA4Macular degenerationMutation detectionSouth Indian populationStargardtYellow white flecks

Identifiers

PMID31934596
PMCPMC6950877
OpenAlexW2998844390

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Registered trials

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