ArticleHorticulture research2020
Diversity of metabolite accumulation patterns in inner and outer seed coats of pomegranate: exploring their relationship with genetic mechanisms of seed coat development.
Article in Horticulture research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Identification and expression analysis of the sucrose synthase gene family in pomegranate (PeerJ · 2022Pooled it
- Integrated Metabolome-Transcriptome Profiling Identifies JrMYB8 as a Repressor of Polyphenol Biosynthesis in Walnut (Plants (Basel, Switzerland) · 2026Article
- Integrated Metabolomics and Targeted Gene Expression Profiling Reveal the Arginine-Anthocyanin Axis in Pomegranate Aril Paleness Disorder.Current issues in molecular biology · 2026Article
- Seed Watermelon (Molecules (Basel, Switzerland) · 2025Article
- A telomere-to-telomere gap-free assembly integrating multi-omics uncovers the genetic mechanism of fruit quality and important agronomic trait associations in pomegranate.Plant biotechnology journal · 2025Article
- Dual regulation of seed coat structure and flavonoids biosynthesis on seed dormancy formation of alfalfa.Plant cell reports · 2025Article
- Genome assembly of pomegranate highlights structural variations driving population differentiation and key loci underpinning cold adaption.Horticulture research · 2025Article
- Widely targeted metabolomics reveal the distribution of primary and secondary metabolites in pomegranate fruit.Food science & nutrition · 2024Article
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- Identification and Functional Analysis of the Promoter of a Leucoanthocyanidin Reductase Gene from Gossypium hirsutum.Molecular biotechnology · 2023Article
- Two major chromosome evolution events with unrivaled conserved gene content in pomegranate.Frontiers in plant science · 2023Article
- Characterization of the ABC Transporter G Subfamily in Pomegranate and Function Analysis ofInternational journal of molecular sciences · 2022Article
- Identification of sugar transporter (SWEET) genes involved in pomegranate seed coat sugar accumulation.3 Biotech · 2022Article
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- Article
- Systematic Analysis and Expression Profiles of the 4-Coumarate: CoA Ligase (4CL) Gene Family in Pomegranate (International journal of molecular sciences · 2022Article
- Metabolite Profiling and Transcriptome Analysis Unveil the Mechanisms of Red-Heart Chinese Fir [Frontiers in plant science · 2022Article
- Integrated Transcriptome and Metabolome Analyses Reveal the Anthocyanin Biosynthesis Pathway inFrontiers in bioengineering and biotechnology · 2022Article
- Combined morphological and multi-omics analyses to reveal the developmental mechanism ofFrontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expanded outer seed coat and the rigid inner seed coat of pomegranate seeds, both affect the sensory qualities of the fruit and its acceptability to consumers. Pomegranate seeds are also an appealing model for the study of seed coat differentiation and development. We conducted nontarget metabolic profiling to detect metabolites that contribute to the morphological differentiation of the seed coats along with transcriptomic profiling to unravel the genetic mechanisms underlying this process. Comparisons of metabolites in the lignin biosynthetic pathway accumulating in seed coat layers at different developmental stages revealed that monolignols, including coniferyl alcohol and sinapyl alcohol, greatly accumulated in inner seed coats and monolignol glucosides greatly accumulated in outer seed coats. Strong expression of genes involved in monolignol biosynthesis and transport might explain the spatial patterns of biosynthesis and accumulation of these metabolites. Hemicellulose constituents and flavonoids in particular accumulated in the inner seed coat, and candidate genes that might be involved in their accumulation were also identified. Genes encoding transcription factors regulating monolignol, cellulose, and hemicellulose metabolism were chosen by coexpression analysis. These results provide insights into metabolic factors influencing seed coat differentiation and a reference for studying seed coat developmental biology and pomegranate genetic improvement.
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