ArticleInternational journal of clinical and experimental pathology2019
Relationship between esophageal cancer-related gene 2 polymorphism and esophageal squamous cell carcinomas in Kazakhs and Hans of Xinjiang.
Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- ECRG2/SPINK7 Tumor Suppressor as Modulator of DNA Damage Response.International journal of molecular sciences · 2024Review
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3 authors at 1 institution in 1 country.
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Abstract
In recent years, many studies have focused on the novel esophageal cancer-related gene 2 (ECRG2), which might be important in esophageal cancer development. The aim of this study is to investigate the relationship between ECRG2 short tandem repeat (STR) polymorphism and susceptibility to esophageal squamous cell carcinomas (ESCCs) in Kazakhs and Hans in Xinjiang. ECRG2 genotypes were detected by PCR-SSCP in 178 cases of esophageal carcinomas and 153 blood samples from the Kazakh and Han population. In Kazakhs and Hans, the frequencies of ECRG2 STR genotypes TCA3/TCA3, TCA4/TCA4, and TCA3/TCA4 were 47.8%/8.7%, 43.5%/67.9%, and 7.1%/25.0% in esophageal carcinomas with metastasis, respectively; and 14.1%/38%, 47.9%/14.3%, and 44.6%/41.1% in carcinomas without metastasis, respectively. A significant difference was observed between the groups with metastasis and without metastasis (Kazakh: χ
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31934184PMC6949829W3027976202What OpenQuestion holds
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