Evidence map›Paper›PMID 31934172›Full record

ArticleInternational journal of clinical and experimental pathology2019

Circ 0001434 RNA reduces inflammation in acute lung injury model through Wnt/β-catenin and NF-κB by miR-625-5p.

Bi Tang, Qingmei Xu, Ling Xuan, Hongju Wang, Heng Zhang, Xiaojing Wang, Pinfang Kang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Crucial Roles of miR-625 in Human Cancer.Frontiers in medicine · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bi TangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Qingmei XuDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Ling XuanDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Hongju WangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Heng ZhangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Xiaojing WangClinical and Basic Provincial Laboratory of Respiratory System Diseases of Anhui Province, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
Pinfang KangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Bengbu Medical College Bengbu, Anhui Province, P. R. China.
First Affiliated Hospital of Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and complicated inflammatory lung diseases. Circ RNAs have emerged as a novel class of gene regulatory molecules that play vital roles in multiple complex diseases, including ALI. In this study, we aimed to identify potential regulators of Circ 0001434 on acute lung injury (ALI) and to explore their roles in lipopolysaccharide (LPS)-induced ALI. In a mouse ALI model, Circ 0001434 expression was effectively down-regulated, compared with the control group. Up-regulation of Circ 0001434 effectively decreased the inflammation of ALI in an

Indexed as

ALICirc 0001434inflammationmiR-625-5pNF-κBWnt/β-catenin

Identifiers

PMID31934172
PMCPMC6949842
OpenAlexW3004579171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.