Evidence map›Paper›PMID 31934171›Full record

ArticleInternational journal of clinical and experimental pathology2019

Distinct expression patterns of aging effects on the UPR

Yaoyan Dun, Zhihao Cheng, Jie Liu, Yuhui Guo, Yumin He, Zhengguo Xiong, Ding Yuan, Changcheng Zhang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yaoyan DunMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Zhihao ChengMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Jie LiuMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Yuhui GuoMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Yumin HeMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Zhengguo XiongMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Ding YuanMedical College of China Three Gorges University Yichang 443002, Hubei, China.
Changcheng ZhangMedical College of China Three Gorges University Yichang 443002, Hubei, China.
China Three Gorges University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have reported that the unfolded protein response of ER (UPR

methodsAging rats had been treated with different doses (10 and 30 mg/kg) of SPJ for 6 months, which were mixed with feed, since they were 18 months old. Then the expressions of GRP78 and three different UPR

conclusionThe study demonstrated that UPR

Indexed as

Agingendoplasmic reticulumintestinesaponins from Panax japonicusunfolded protein response

Identifiers

PMID31934171
PMCPMC6949813
OpenAlexW3006974042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.