Evidence map›Paper›PMID 31934128›Full record

ArticleInternational journal of clinical and experimental pathology2019

The expressions of autotaxin-lysophosphatidate signaling-related proteins in metastatic breast cancer.

Su Jung Shim, Eunah Shin, Choong-Sik Lee, Ja Seung Koo

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Autotaxin: An Early Warning Biomarker for Acute-on-chronic Liver Failure.Journal of clinical and translational hepatology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Su Jung ShimDepartment of Radiation Oncology, Eulji Hospital, Eulji University School of Medicine Seoul, Korea.
Eunah ShinDepartment of Pathology, CHA Gangnam Medical Center, CHA University School of Medicine Seoul, Korea.
Choong-Sik LeeDepartment of Pathology, Chungnam National University College of Medicine Daejun, Korea.
Ja Seung KooDepartment of Pathology, Yonsei University College of Medicine Seoul, South Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated the expression of autotaxin-lysophosphatidate signaling-related proteins and the clinical implications for metastatic breast cancer.

methodsWe constructed tissue microarrays (TMA) with 126 cases of metastatic breast cancer [31 (24.6%) bone metastases, 36 (28.6%) brain metastases, 11 (8.7%) liver metastases, and 48 (38.1%) lung metastasis], and we conducted immunohistochemical staining for the autotoxin-lysophosphatidate signaling-related proteins ATX, LPA

resultsStromal ATX (P = 0.006) and LPA

conclusionAmong autotoxin-lysophosphatidate signaling-related proteins, stromal ATX was highly expressed in bone metastases, and LPA

Indexed as

Autotaxinbreast cancerlysophosphatidate receptormetastasis

Identifiers

PMID31934128
PMCPMC6949729
OpenAlexW3008221654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.