Evidence map›Paper›PMID 31934118›Full record

ArticleInternational journal of clinical and experimental pathology2019

Increased CDK4 protein expression predicts a poor prognosis in mucosal melanoma associated with the p16

Fang Wang, Guorong Chen, M J Quinn, Suidan Chen, Xiuhuan Ji, Yangping Shentu, Yangyang Li

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Exploration of Therapeutic Targets Using CDK4 Inhibitors for Head and Neck Mucosal Melanoma.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  2. Prognostic Implications of MDM2 and CDK4 Co-amplification in Liposarcoma: Insights from FISH analysis for Translational Oncology.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fang WangDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Guorong ChenDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
M J QuinnDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Suidan ChenDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Xiuhuan JiDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Yangping ShentuDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Yangyang LiDepartment of Pathology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal melanoma (MM) occurs in non-cutaneous mucosal sites, e.g., the head and neck or the lower genital tract; it is a rare and aggressive neoplasm with a poor prognosis. To date, few prognostic markers of MM have been well-defined. The aim of this study is to clarify the prognostic value of the cell-cycle regulatory proteins (CDK4, pRb and CyclinD1, p16) which are associated with the p16

Indexed as

CDK4 proteinmucosal melanomaprognosis

Identifiers

PMID31934118
PMCPMC6949700
OpenAlexW3019499151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.