ArticleInternational journal of clinical and experimental pathology2019
Spindle cell lipoma: clinicopathologic characterization of 40 cases.
Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 36 citations in OpenAlex.
- A Case of Rare Adipocytic Tumor of the Tongue: Lipoblastoma-Like Tumor With RB1 Gene Deletion.Cureus · 2025Article
- A case report unveiling spindle cell lipoma.Radiology case reports · 2025Article
- Eyelid Spindle Cell Lipoma: Case Report and Review of Three Patients in Literature.Clinical case reports · 2025Article
- Myxolipoma of the Popliteal Fossa: A Rare Tumor Case Report.Reports (MDPI) · 2024Article
- Article
- Collision tumor of spindle cell lipoma arising from perirenal tissue and acquired cystic disease-associated renal cell carcinoma: A rare case report.IJU case reports · 2023Article
- Unusual lipid poor spindle cell lipoma.BMJ case reports · 2023Article
- Intradermal Low-Fat Spindle Cell Lipoma: A Case Report.Annals of dermatology · 2023Article
- A case report of spindle cell lipoma.Annals of medicine and surgery (2012) · 2022Article
- Spindle cell lipoma: An uncommon variant of lipoma affecting the foot sole.Clinical case reports · 2022Article
- Case report: Atypical spindle cell/pleomorphic lipomatous tumor masquerading as a myxoid liposarcoma or intramuscular myxoma.Frontiers in oncology · 2022Article
- Histological and Ultrastructural Description of Benign Adipocytic Tumors in Farmed Striped Sea Bream (Animals : an open access journal from MDPI · 2021Article
- Esophageal spindle cell lipoma.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Spindle Cell Lipoma and Pleomorphic Lipoma: An Update and Review.Cancer diagnosis & prognosisReview
- Well-differentiated Spindle Cell Liposarcoma of the Larynx: A Rare Case Report and Review of Literature.In vivo (Athens, Greece)Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn view of the existence of multifarious pathologic subtypes of spindle cell lipoma (SCL), which is easily misdiagnosed as other benign and malignant soft tissue tumors, we performed this study and aimed to better define the category of SCL.
methodsWe collected and analyzed 40 cases of SCL with complete clinical and pathologic information from January 2010 to December 2018. Clinical and histopathologic analyses of SCL were performed, as well as immunohistochemical staining and fluorescence in situ hybridization (FISH) using probes for
resultsIn 40 cases, the male to female ratio was 3.4:1, and the mean age was 54 years old. SCL of our study included six pathologic subtypes: classic (25/40), fibrous (4/40), myxoid (4/40), low-fat (3/40), pseudoangiomatous (2/40), and fat-rich (2/40) changes. Microscopically, SCL showed distinctive morphology, with uniform spindle cells and a variably adipocytic component. The spindle cells were bland in morphology, without prominent atypia or pleomorphism, set in a myxoid or fibrous matrix. Immunohistochemically, CD34 and vimentin were positive in spindle cells, and spindle cells of 6 cases also expressed S-100 protein. FISH analysis of 10 cases revealed that heterozygous deletion of
conclusionsSCL is a rare benign lipoma, and the proportion of spindle cells and adipocytic component varies, which may form various pathologic changes. The diagnosis needs to be combined with clinicopathologic features, immunophenotypes, and genetics. It has to be differentiated from mammary-type myofibroblastoma, cellular angiolipoma, solitary fibrous tumor, and myxoid liposarcoma.
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Identifiers
31934089PMC6949558W3005757377What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.