Evidence map›Paper›PMID 31934064›Full record

ArticleInternational journal of clinical and experimental pathology2019

BDNF gene polymorphism and serum level correlate with liver function in patients with hepatitis B-induced cirrhosis.

Hong-Chun Shu, Jia Hu, Xiao-Bo Jiang, Hui-Qiu Deng, Kun-He Zhang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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  12. A Preliminary Prospective Study on the Association of Polymorphisms inCancer control : journal of the Moffitt Cancer Center
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hong-Chun ShuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Jiangxi Institute of Gastroenterology & Hepatology Nanchang 330006, Jiangxi Province, PR China.
Jia HuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Jiangxi Institute of Gastroenterology & Hepatology Nanchang 330006, Jiangxi Province, PR China.
Xiao-Bo JiangDepartment of Gastroenterology, Shangrao People's Hospital Shangrao 320834, Jiangxi Province, PR China.
Hui-Qiu DengDepartment of Gastroenterology, Shangrao People's Hospital Shangrao 320834, Jiangxi Province, PR China.
Kun-He ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Jiangxi Institute of Gastroenterology & Hepatology Nanchang 330006, Jiangxi Province, PR China.
Shangrao Normal University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate the correlation of serum brain-derived neurotrophic factor (BDNF) level and its gene polymorphism with liver function classification in patients with hepatitis B virus (HBV) induced liver cirrhosis. A total of 182 patients with HBV induced liver cirrhosis were collected as a case group, and 186 healthy subjects in the same period were used as the control group. ELISA measured serum BDNF levels. Polymerase chain reaction-restriction fragment length polymorphism was used to detect rs6265 (A/G) and rs10835210 (A/C) in the

Indexed as

Brain-derived neurotrophic factorChild-Pugh classificationcirrhosisfrequencygene polymorphismhaplotypeliver functionrisk

Identifiers

PMID31934064
PMCPMC6949635
OpenAlexW3003920265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.