Evidence map›Paper›PMID 31933979›Full record

ArticleInternational journal of clinical and experimental pathology2019

miR-539-3P inhibits proliferation and invasion of gastric cancer cells by targeting CTBP1.

Jia Zhou, Mingqi Su, Hui Zhang, Jialiang Wang, Ying Chen

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jia ZhouDepartment of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai , China.
Mingqi SuDepartment of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai , China.
Hui ZhangDepartment of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai , China.
Jialiang WangDepartment of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai , China.
Ying ChenDepartment of Oncology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai , China.
Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is the fifth most lethal carcinoma in the world. Genetic and epigenetic factors transform the normal cells into malignant cells and lead to tumor development. MicroRNA (miRNA), a small non-coding RNA which functions in RNA silencing and post-transcriptional regulation of gene expression, is closely associated with cancer initiation and propagation, including stomach cancer. In this study, for the first time, we report miR-539-3P, as a tumor suppressor, was down-regulated in gastric cancer both

Indexed as

CTBP1epithetial to mesenchymal transition (EMT)Gastric cancerinvasionmalignant proliferationmiR-539

Identifiers

PMID31933979
PMCPMC6947129
OpenAlexW3005712129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.