Evidence map›Paper›PMID 31933867›Full record

ArticleInternational journal of clinical and experimental pathology2019

Radionuclide imaging and therapy in malignant melanoma after survivin promoter-directed sodium iodide symporter gene transfer in vitro and in vivo.

Zhen Zhao, Rui Huang, Huawei Cai, Bin Liu, Yu Zeng, Anren Kuang

Abstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhen ZhaoDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Rui HuangDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Huawei CaiDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Bin LiuDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Yu ZengDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Anren KuangDepartment of Nuclear Medicine, West China Hospital of Sichuan University Chengdu, Sichuan, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to develop a gene expression targeting method specific for the imaging and therapy of malignant melanoma A375 cells using the sodium iodide symporter gene under control of the survivin promoter (Ad-Sur-NIS). When compared to control Ad-Sur-GFP-treated cells, Ad-Sur-NIS resulted in significantly higher iodide uptake in all 50, 100, or 150 MOIs examined cells (P<0.001). In vitro clonogenic assay showed the inhibition rates induced by

Indexed as

Malignant melanomapertechnetate imagingradioiodine therapysodium iodide symportersurvivin

Identifiers

PMID31933867
PMCPMC6945074
OpenAlexW3015089281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.