Evidence map›Paper›PMID 31933833›Full record

ArticleInternational journal of clinical and experimental pathology2019

Proliferative myositis and nodular fasciitis: a retrospective study with clinicopathologic and radiologic correlation.

Siyuan Gan, Dongqi Xie, Haixia Dai, Zhi Zhang, Xiaoqing Di, Rujia Li, Linlang Guo, Yanqin Sun

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Siyuan GanDepartment of Pathology, Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Dongqi XieDepartment of Ultrasound, The Second Affiliated Hospital of Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Haixia DaiDepartment of Ultrasound, The Affiliated Hospital of Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Zhi ZhangDepartment of Thyroid and Mammary Vascular Surgery, The Affiliated Hospital of Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Xiaoqing DiDepartment of Pathology, The Affiliated Hospital of Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Rujia LiDepartment of Pathology, Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Linlang GuoDepartment of Pathology, Zhu Jiang Hospital, Southern Medical University Haizhu District, Guangzhou 510280, Guangdong, P. R. China.
Yanqin SunDepartment of Pathology, Guangdong Medical University Xiashan District, Zhanjiang 524023, Guangdong, P. R. China.
Guangdong Medical College · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proliferative myositis (PM) and nodular fasciitis (NF) are two diseases easily misdiagnosed as cancer, often promoting unnecessary invasive procedures. To make accurate diagnoses of PM and NF and for the differential diagnosis between them, we performed a retrospective study to evaluate the roles of the clinical, radiologic, and pathologic characteristics of PM and NF. With an emphasis on the clinicopathologic and radiologic characteristics, we conducted a retrospective study of 8 cases of PM and 64 cases of NF that were diagnosed between 2012 and 2018. According to MRI findings, the lesions of PM and NF appeared as homogeneous masses with homogenous hypointensity or isointensity on T1-weighted images and as moderately or markedly hyperintense signals on T2-weighted images compared to skeletal muscle. In terms of histopathologic features, the differences between PM and NF mainly consisted of the presence of ganglion-like myofibroblasts with vesicular nuclei and basophilic cytoplasm in PM. The areas abundant in myxoid stroma with inflammatory infiltration that did not have abundant ganglion-like cells suggest NF. Immunohistochemically, the spindle-shaped cells of PM stained positive for smooth muscle actin (SMA), while the ganglion-like cells were negative. The spindle-shaped cells of NF showed diffuse expression of SMA, calponin, and vimentin. Our comprehensive study further demonstrated that PM and NF had a wide clinicopathologic and radiologic spectrum. Correlation with the clinical, radiologic and pathologic characteristics may help clinicians and pathologists make accurate diagnoses.

Indexed as

clinical characteristicsnodular fasciitispathologyProliferative myositisradiological characteristics

Identifiers

PMID31933833
PMCPMC6949867
OpenAlexW3006000773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.