Evidence map›Paper›PMID 31933730›Full record

ArticleInternational journal of clinical and experimental pathology2019

MiR-381 functions as a tumor suppressor in gastric cancer by targeting ROCK2.

Yilin Xie, Jing Qi, Congbo Zhu, Dingmin Zhao, Guoqing Liao

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yilin XieDepartment of Endoscopy Center, The First Affiliated Hospital of Xiamen University Xiamen, P. R. China.
Jing QiDepartment of Gastrointestinal Surgery, Xiangya Hospital of Central South University Changsha, Hunan Province, P. R. China.
Congbo ZhuDepartment of Gastrointestinal Surgery, Xiangya Hospital of Central South University Changsha, Hunan Province, P. R. China.
Dingmin ZhaoDepartment of Gastrointestinal Surgery, Xiangya Hospital of Central South University Changsha, Hunan Province, P. R. China.
Guoqing LiaoDepartment of Gastrointestinal Surgery, Xiangya Hospital of Central South University Changsha, Hunan Province, P. R. China.
Central South University · CNFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MiR-381 has been reported to be deregulated in many different types of human cancers. However, the clinical significance and function of miR-381 in gastric cancer (GC) remains unclear. Based on real-time quantitative PCR (RTq-PCR) analysis, we found that miR-381 was frequently lost or downregulated in GC tissues and cell lines, and decreased miR-381 was correlated with GC tumor size (

Indexed as

cell invasioncell migrationcell proliferationgastric cancermiR-381ROCK2

Identifiers

PMID31933730
PMCPMC6944001
OpenAlexW2998975032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.