Evidence map›Paper›PMID 31933480›Full record

ArticleeLife2020

Biochemical reconstitution of branching microtubule nucleation.

Raymundo Alfaro-Aco, Akanksha Thawani, Sabine Petry

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Mechanisms underlying spindle assembly and robustness.Nature reviews. Molecular cell biology · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Augmin is a Ran-regulated spindle assembly factor.The Journal of biological chemistry · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. How Microtubules Build the Spindle Branch by Branch.Annual review of cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raymundo Alfaro-AcoDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0003-4196-3797
Akanksha ThawaniDepartment of Chemical and Biological Engineering, Princeton University, Princeton, United States.ORCID 0000-0003-4168-128X
Sabine PetryDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0002-8537-9763

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007388 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 1985 to 2022
$27.4M
Building the Chromosome Segregation Machinery from ScratchDP2GM123493 · NIGMS · PRINCETON UNIVERSITY · PI PETRY, SABINE · 2016 to 2016
$2.4M
American Heart Association 17PRE33660328David and Lucile Packard Foundation 2014-40376NIGMS NIH HHS DP2 GM123493NIGMS NIH HHS T32 GM007388
6 · The paper itself

Abstract

Microtubules are nucleated from specific locations at precise times in the cell cycle. However, the factors that constitute these microtubule nucleation pathways and their mode of action still need to be identified. Using purified

Indexed as

Gene Expression RegulationAnimalsBrainCattleCell Cycle ProteinsEscherichia coliHumansMicroscopy, FluorescenceMicrotubule-Associated ProteinsMicrotubule ProteinsMicrotubulesMitosisMultiprotein ComplexesSpindle ApparatusTubulinXenopus laevisaugmin protein complex, XenopusCell Cycle ProteinsMicrotubule-Associated ProteinsMicrotubule ProteinsMultiprotein ComplexesTPX2 protein, XenopusTubulinXenopus Proteinsbiochemistrybranchingcell biologychemical biologymicrotubulenucleationreconstitutionxenopus

Identifiers

PMID31933480
PMCPMC6959992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.