ArticleEndocrine2020
Ultrasound risk stratification systems for thyroid nodule: between lights and shadows, we are moving towards a new era.
Article in Endocrine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Head-to-head comparison of American, European, and Asian TIRADSs in thyroid nodule assessment: systematic review and meta-analysis.European thyroid journal · 2024Pooled it
- Suboptimal accuracy of ultrasound and ultrasound-based risk stratification systems in detecting medullary thyroid carcinoma should not be overlooked. Findings from a systematic review with meta-analysis.Clinical endocrinology · 2022Pooled it
- The ultrasound risk stratification systems for thyroid nodule have been evaluated against papillary carcinoma. A meta-analysis.Reviews in endocrine & metabolic disorders · 2021Pooled it
- A randomized controlled trial comparing non-selective versus selective TIRADS-based cytology in thyroid cancer diagnostics.The British journal of surgery · 2026Trial
- Cytology-Radiology Correlation Series: Thyroid cytopathology.Cancer cytopathology · 2025Review
- Performance of ACR-TIRADS in assessing thyroid nodules does not vary according to patient age.Hormones (Athens, Greece) · 2024Article
- Meaning of ACR-TIRADS recommendation in favor of follow-up rather than FNAC in thyroid nodules.Updates in surgery · 2024Article
- Comparative Analysis of AI-SONICTM Thyroid System and Six Thyroid Risk Stratification Guidelines in Papillary Thyroid Cancer: A Retrospective Cohort Study.Therapeutics and clinical risk management · 2024Article
- Review
- The Future of Thyroid Nodule Risk Stratification.Endocrinology and metabolism clinics of North America · 2022Review
- Editorial: Experiences and advances in endocrinology point-of-care ultrasound (POCUS).Frontiers in endocrinology · 2022Article
- Article
- Thyroid Nodule Characterization: How to Assess the Malignancy Risk. Update of the Literature.Diagnostics (Basel, Switzerland) · 2021Review
- Prediction of thyroid nodule histopathology by expert ultrasound evaluation.Endocrine connections · 2021Article
- Observational
- EU-TIRADS-Based Omission of Fine-Needle Aspiration and Cytology from Thyroid Nodules Overlooks a Substantial Number of Follicular Thyroid Cancers.International journal of endocrinology · 2021Article
- Review
- FNA indication according to ACR-TIRADS, EU-TIRADS and K-TIRADS in thyroid incidentalomas atJournal of endocrinological investigation · 2020Article
- [Nodular goiter].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- The Added Value of Operator's Judgement in Thyroid Nodule Ultrasound Classification Arising From Histologically Based Comparison of Different Risk Stratification Systems.Frontiers in endocrinology · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ultrasound (US) has long played a major role in the assessment of thyroid nodules and their risk of malignancy, and its importance has been further enhanced over the past decade by the development of a number of US-based risk stratification systems (US-RSSs), referred to in some cases as TIRADS (Thyroid Imaging Reporting And Data Systems). The high-risk categories of all currently available US-RSSs display strong associations to cytological diagnostic classes of "malignant/suspicious-for-malignancy" and the low-risk classes are clearly associated to "not neoplastic/benign" cytology. The introduction of these systems has elevated the diagnostic performance of US to a level approaching that of fine-needle aspiration (FNA) cytology. The time seems ripe to exploit this new level of accuracy to reduce the number of FNAs for nodules likely to be benign (i.e., sonographically classified as low-risk with no suspicious clinical features). In the near future, US-RSS could also become the main tool for diagnosing papillary thyroid cancers. The establishment of a new "international TIRADS"-currently in progress-will be critical to guide us towards a new era.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.