Evidence map›Paper›PMID 31933076›Full record

ArticleEnvironmental science and pollution research international2020

Transcriptional and biochemical biomarker responses in a freshwater mussel (Anodonta anatina) under environmentally relevant Cu exposure.

Gustaf Magnus Oskar Ekelund Ugge, Annie Jonsson, Björn Olsson, Robert Sjöback, Olof Berglund

Open access · hybridAbstract read
In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Proteomic and in silico characterization of stress-responsive proteins in the prawn penaeus indsicus under sublethal copper toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gustaf Magnus Oskar Ekelund UggeDepartment of Biology, Lund University, Sölvegatan 37, 223 62, Lund, Sweden. gustaf.ekelund_ugge@biol.lu.se.ORCID http://orcid.org/0000-0002-2418-1163
Annie JonssonSchool of Bioscience, University of Skövde, Högskolevägen 3, 541 28, Skövde, Sweden.
Björn OlssonSchool of Bioscience, University of Skövde, Högskolevägen 3, 541 28, Skövde, Sweden.
Robert SjöbackTATAA Biocenter, Odinsgatan 28, 411 03, Gothenburg, Sweden.
Olof BerglundDepartment of Biology, Lund University, Sölvegatan 37, 223 62, Lund, Sweden.
Lund University · SEUniversity of Skövde · SETataa Biocenter (Sweden) · SE

Funding

ALS Scandinavia Toxicon AB -Stiftelsen för Kunskaps- och Kompetensutveckling -TATAA Biocenter -
6 · The paper itself

Abstract

Molecular biomarkers, like gene transcripts or enzyme activities, are potentially powerful tools for early warning assessment of pollution. However, a thorough understanding of response and baseline variation is required to distinguish actual effects from pollution. Here, we assess the freshwater mussel Anodonta anatina as a biomarker model species for freshwater ecosystems, by testing responses of six transcriptional (cat, gst, hsp70, hsp90, mt, and sod) and two biochemical (AChE and GST) biomarkers to environmentally relevant Cu water concentrations. Mussels (n = 20), collected from a stream free from point source pollution, were exposed in the laboratory, for 96 h, to Cu treatments (< 0.2 μg/L, 0.77 ± 0.87 μg/L, and 6.3 ± 5.4 μg/L). Gills and digestive glands were extracted and analyzed for transcriptional and biochemical responses. Biological and statistical effect sizes from Cu treatments were in general small (mean log

Indexed as

AnodontaWater Pollutants, ChemicalAnimalsBiomarkersEcosystemFemaleFresh WaterGillsMaleBiomarkersWater Pollutants, ChemicalBivalveEffect sizeGene expressionResponse variabilityRT-qPCRSex effects

Identifiers

PMID31933076
PMCPMC7089896
OpenAlexW2999988289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.