Evidence map›Paper›PMID 31932964›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

Cervical muscle diseases are associated with indefinite and various symptoms in the whole body.

Takayoshi Matsui, Kazuhiro Hara, Takamasa Kayama, Makoto Iwata, Nobuyuki Shitara, Shuntaro Hojo, Yuzo Endo, Hideoki Fukuoka, Noriko Yoshimura, Hiroshi Kawaguchi

Abstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Tissue specific signature of HHV-6 infection in ME/CFS.Frontiers in molecular biosciences · 2022
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Takayoshi MatsuiTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Kazuhiro HaraMatsui Hospital, Kan-nonji 739, Kagawa, 768-0013, Japan.
Takamasa KayamaTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Makoto IwataTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Nobuyuki ShitaraTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Shuntaro HojoTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Yuzo EndoTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Hideoki FukuokaTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan.
Noriko YoshimuraUniversity of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, Japan.
Hiroshi KawaguchiTokyo Neurological Center, Toranomon 4-1-17, Minato-ku, Tokyo, 105-0001, Japan. kawaguchi0126@gmail.com.
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with various and indefinite symptoms in the whole body occasionally have coincident with stiffness or tenderness of the cervical muscles. This prospective case series examined the effect of local modulation of the cervical muscles in patients with cervical disorders reporting indefinite whole-body symptoms.

methodsA total of 1863 hospitalized patients with cervical disorders accompanying three or more indefinite whole-body symptoms, who were resistant to outpatient care, were enrolled in this study for 12 years. All patients underwent daily physical therapies to the cervical muscles during hospitalization. Self-rated records on the medical interview sheets documenting 30 representative symptoms including cervical/shoulder pain or stiffness and 28 representative indefinite whole-body symptoms at admission and discharge were compared across the population.

resultsThe number of symptoms decreased significantly with the local modulation of the cervical muscles during hospitalization. All of the 28 indefinite whole-body symptoms at admission showed recovery rates greater than 50% at discharge. The mean number of symptoms decreased significantly from 17.8 at admission to 7.4 at discharge (p < 0.0001). The percentages of patients reporting 10 or more symptoms were 91.1% and 29.3% at admission and discharge, respectively. Moreover, 8.2% of patients reported no residual symptoms at discharge.

conclusionCervical muscle lesions may contribute to indefinite whole-body symptoms, possibly through dysfunction of the parasympathetic nervous system in the muscles. Local modulation of cervical muscles could lead to a breakthrough in the management of patients with indefinite whole-body symptoms. TRIAL REGISTRATION ID: UMIN000035445. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

HospitalizationPatient DischargeHumansMusclesNeckProspective StudiesCervical disorderCervical muscleIndefinite symptomParasympathetic nerveTreatment

Identifiers

PMID31932964
OpenAlexW2998797031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.